2014
DOI: 10.1002/cncr.28624
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Phase angle for prognostication of survival in patients with advanced cancer: Preliminary findings

Abstract: Background Accurate survival prediction is essential for decision-making in cancer therapies and care planning. Objective physiologic measures may improve the accuracy of prognostication. In this prospective study, we determined the association of phase angle, hand grip strength, and maximal inspiratory pressure with overall survival in patients with advanced cancer. Methods We enrolled hospitalized patients with advanced cancer who were seen by palliative care for consultation. We collected information on p… Show more

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Cited by 101 publications
(124 citation statements)
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“…Some are relevant and already have confirmed significance as prognostic indicators: the Palliative Prognostic Index, serum albumin, lean body mass. In the present study, only unadjusted pa values were used as described by Hui et al 36 , who confirmed that the unadjusted pa and the sga are both significantly associated with survival and correlate with each other. Their final recommendation was that the unadjusted pa provides valuable information and can be used as prognostic factor.…”
Section: Discussionsupporting
confidence: 73%
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“…Some are relevant and already have confirmed significance as prognostic indicators: the Palliative Prognostic Index, serum albumin, lean body mass. In the present study, only unadjusted pa values were used as described by Hui et al 36 , who confirmed that the unadjusted pa and the sga are both significantly associated with survival and correlate with each other. Their final recommendation was that the unadjusted pa provides valuable information and can be used as prognostic factor.…”
Section: Discussionsupporting
confidence: 73%
“…The study by Hui et al 36 confirmed that pa is a significant predictor of poor survival, independent of established prognostic factors in an advanced cancer setting. The median survivals for patients with pas of 2-2.9, 3-3.9, 4-4.9, 5-5.9, and 6 or more were 35 days, 54 days, 112 days, 134 days, and 220 days respectively.…”
Section: Discussionmentioning
confidence: 88%
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“…To date, a variety of biomarkers such as pro‐inflammatory markers have been used to diagnose cachexia, and body composition variables and PA have been frequently used as prognostic variables for survival in cancer patients with cachexia 9, 10. PA, which is a composite indicator of the resistance and reactance representing fluid distribution in cells and cell wall integrity,11 can be measured via bioelectrical impedance analysis (BIA).…”
Section: Introductionmentioning
confidence: 99%