Pharyngeal Gonorrhea in Heterosexual Male and Female Sex Partners of Persons With Gonorrhea

McLaughlin, Stephanie E.; Golden, Matthew R.; Soge, Olusegun O.; Berzkalns, Anna; Thibault, Christina; Barbee, Lindley A

doi:10.1097/olq.0000000000001760

Cited by 8 publications

(8 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…kissing and oral-genital sex) is often not collected and individuals may not feel comfortable discussing this with healthcare providers outside STI clinics [98]. A few STI clinics have changed their policy to include selective oropharyngeal STI screening in women and heterosexual men [99,100,101 ▪ ,102,103 ▪ ,104]. Studies found that 18–20% of heterosexual men and 35–46% of women who reported sexual contacts with partners with gonorrhoea tested positive for N. gonorrhoeae at the oropharynx [100,101 ▪ ,102].…”

Section: Screening For Oropharyngeal Infectionsmentioning

confidence: 99%

“…A few STI clinics have changed their policy to include selective oropharyngeal STI screening in women and heterosexual men [99,100,101 ▪ ,102,103 ▪ ,104]. Studies found that 18–20% of heterosexual men and 35–46% of women who reported sexual contacts with partners with gonorrhoea tested positive for N. gonorrhoeae at the oropharynx [100,101 ▪ ,102]. More importantly, a substantial proportion of oropharyngeal infections would have been unidentified in heterosexual men (36–89%) and women (19–40%) if urogenital-only testing were performed [100,101 ▪ ].…”

Section: Screening For Oropharyngeal Infectionsmentioning

confidence: 99%

“…Studies found that 18–20% of heterosexual men and 35–46% of women who reported sexual contacts with partners with gonorrhoea tested positive for N. gonorrhoeae at the oropharynx [100,101 ▪ ,102]. More importantly, a substantial proportion of oropharyngeal infections would have been unidentified in heterosexual men (36–89%) and women (19–40%) if urogenital-only testing were performed [100,101 ▪ ]. Unidentified and untreated oropharyngeal chlamydia may lead to the risk of transmission between anatomical sites within the individual.…”

Section: Screening For Oropharyngeal Infectionsmentioning

confidence: 99%

See 2 more Smart Citations

STI pathogens in the oropharynx: update on screening and treatment

Chow,

Fairley,

Kong

2023

Current Opinion in Infectious Diseases

View full text Add to dashboard Cite

Purpose of review The rise in antimicrobial resistance in several STI pathogens such as Neisseria gonorrhoeae has become a public health threat as only one first-line treatment remains. Reducing screening interval for gonorrhoea and chlamydia in high-prevalence populations has been proposed to address antimicrobial stewardship, but this remains controversial. This review aimed to revisit the epidemiology of infections at the oropharynx and review the current screening recommendations and treatment guidelines in different populations. Recent findings Emerging evidence suggests that the oropharynx is the primary anatomical site for gonorrhoea transmission but maybe not for chlamydia transmission. Most international guidelines recommend 3-monthly oropharyngeal gonorrhoea and chlamydia screening for high-prevalence populations (e.g. men who have sex with men) but not low-prevalence populations (e.g. heterosexuals) given the clinical and public health benefits of screening in low-prevalence populations are still unclear. Doxycycline remains the first-line treatment for oropharyngeal chlamydia in most guidelines. However, some countries have moved from dual therapy (ceftriaxone and azithromycin) to monotherapy (ceftriaxone) for oropharyngeal gonorrhoea treatment to address antimicrobial stewardship. Summary The transmission of gonorrhoea and chlamydia is still not fully understood. Further work will be required to evaluate the benefits and harms of reducing screening in high-prevalence populations.

show abstract

Section: Screening For Oropharyngeal Infectionsmentioning

confidence: 99%

Section: Screening For Oropharyngeal Infectionsmentioning

confidence: 99%

Section: Screening For Oropharyngeal Infectionsmentioning

confidence: 99%

See 1 more Smart Citation

STI pathogens in the oropharynx: update on screening and treatment

Chow,

Fairley,

Kong

2023

Current Opinion in Infectious Diseases

View full text Add to dashboard Cite

show abstract

“…Pharyngeal gonococcal infection and thyroglossal duct cysts share a cryptic clinical feature commonly typified by asymptomatic presentation. 2,[13][14][15][16][17] A noteworthy and unique aspect in the 2 cases arises from the intersection of these 2 conditions in the same individual that allowed for the fortuitous discovery of both diagnoses, as each abnormality in isolation would have likely escaped detection.…”

Section: Case Reportmentioning

confidence: 99%

Thyroglossal Duct Cyst Infection Caused by Neisseria gonorrhoeae: An Unusual Complication of Pharyngeal Gonorrhea

Roberts,

Johnson,

Lee

2023

Sexual Trans Dis

View full text Add to dashboard Cite

Neisseria gonorrhoeae is a human obligate pathogen whose clinical expression of disease ranges from localized genital infection to involvement of extragenital sites such as the conjunctiva and throat. We describe the second case of a thyroglossal duct abscess due to N. gonorrhoeae, an uncommon complication of pharyngeal gonococcal infection. The fortuitous occurrence in the same individual of these 2 conditions that both exhibit an occult clinical presentation likely accounts for rarity of this infection. We discuss the pertinent gonococcal and host factors that underlie the clinical manifestations of this infection. A particular focus is the fundamental role that the binding of the gonococcal opacity-associated protein to the ubiquitous human carcinoembryonic cell adhesion molecule plays in the pathogenesis of pharyngeal gonorrhea.

show abstract

“…Studies are needed to determine whether and to what extent pharyngeal gonorrhea exists among kissing-only youth. McLaughlin and colleagues 20 reported that pharyngeal gonorrhea is common (~30% prevalence) among heterosexual men and women who have been exposed to NG and suggested that studies are needed of the prevalence of pharyngeal gonorrhea among heterosexual men and women more generally, not just among those exposed to NG.…”

mentioning

confidence: 99%