Pharyngeal Gonorrhea in Female Sex Workers: Response to a Single 2-g Dose of Azithromycin

Abstract

A high carriage rate of gonococci in the throat and a low rate of condom use in oral sex were documented among sex workers in Tel Aviv. A single 2 g dose of azithromycin was very effective in eradicating gonococci from the throat.

Failure to detect Mycoplasma genitalium in the pharynges of female sex workers in Japan

“…19 In a study from Israel, the prevalence was 9.0%. 20 In a study from Japan, the prevalence rates of pharyngeal infections with N. gonorrhoeae and C. trachomatis were 13.8% and 6.9%, respectively. 21 In another study from Japan, the prevalence of C. trachomatis in the pharynx was 22.5%.…”

Sexually transmitted infections among brothel-based sex workers in Tel-Aviv area, Israel: high prevalence of pharyngeal gonorrhoea

“…The women were offered presumptive treatment with azithromycin (the outcome of the treatment was published elsewhere). 4 Throat swabs were transported in charcoal transport medium and streaked within a few hours onto New York City agar (Hy Laboratories, Ltd, Rehovot, Israel). The identity of gonococcal isolates was confirmed with the API-NH system for the identification of Neisseria and Haemophilus spp (BioMerieux, Lyon, France).…”

The Epidemiology of Gonorrhea Among Men Who Have Sex With Men in Stockholm, Sweden, 1990–2004

“…Azithromycin (an oral macrolide) has been suggested as an alternative if a oral treatment is preferred [118,119]; only two cases in paper III were infected with a strain with decreased susceptibility to this drug. However, azithromycin is not recommended in international treatment guidelines for gonorrhoea [60,120], because the 1-g. dose (recommended for treatment of chlamydia) has low efficacy for gonorrhoea and the 2-g. dose causes gastrointestinal intolerance in many patients [121].…”