Pharmacotherapeutic closure of a uveitic macular hole persisting after vitrectomy

Shukla, Dhananjay; Dhawan, Anuradha

doi:10.4103/0301-4738.82018

Cited by 12 publications

(7 citation statements)

References 6 publications

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“…Macular holes secondary to uveitis are known to occur rarely, and relatively few cases have been reported. 2 – 6 Full-thickness macular hole formation secondary to pars planitis has only been reported twice, 2 , 3 and retinal detachment resulting from a postuveitic macular hole has been reported twice. 4 , 5 Georgalas et al 4 and Al-Dhibi et al 5 described a rhegmatogenous retinal detachment due to a macular hole, but in those reports, the underlying pathology was Behçet’s panuveitis, and silicone oil was used as endotamponade.…”

Section: Discussionmentioning

confidence: 99%

“…Development of a full-thickness macular hole secondary to pars planitis has only been reported twice in the literature. 2 , 3 We report a case of a young patient with pars planitis diagnosed with rhegmatogenous retinal detachment due to a macular hole, who was treated with vitrectomy, internal limiting membrane peeling, and C 3 F 8 endotamponade.…”

Section: Introductionmentioning

confidence: 99%

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Rhegmatogenous retinal detachment due to a macular hole in a patient with pars planitis: a case report

Stavrakas¹,

Androu²,

Tranos³

et al. 2014

TCRM

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We report a rare case of rhegmatogenous retinal detachment due to a full-thickness macular hole in a young patient with pars planitis. This study was an interventional case report. A 38-year-old Asian man presented with acute reduction of vision in his left eye. His past ocular history revealed a precedent of two intravitreal steroid injections in his left eye, and fundoscopy revealed a total bullous retinal detachment along with 360° snowbanking at the pars plana. Precise preoperative visualization of the posterior pole was impossible due to a dense nuclear cataract. During surgery, an unexpected full-thickness macular hole with no associated epiretinal membrane was observed, which resulted in the retinal detachment. This case of chronic pars planitis complicated with a full-thickness macular hole resulting in retinal detachment was successfully treated with vitrectomy, internal limiting membrane peeling, and perfluoropropane tamponade. Visual acuity improved from hand movements to 6/36 Snellen at 12 months postsurgery. This case report illustrates the rare but possible association between pars planitis with macular hole formation and subsequent retinal detachment, underlying the beneficiary outcome of vitrectomy surgery both diagnostically and therapeutically.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Rhegmatogenous retinal detachment due to a macular hole in a patient with pars planitis: a case report

Stavrakas¹,

Androu²,

Tranos³

et al. 2014

TCRM

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“…The literature reports 55 cases of macular hole secondary to posterior uveitis (Table 1): 35 Behcet's disease [5-11], 3 idiopathic intermediate uveitis [9], 2 idiopathic posterior uveitis [9], 1 bilateral intermediate uveitis [12], 2 Bartonella henselae [13,14], 2 toxoplasmosis [15,16], 2 Vogt-Koyanagi-Harada [17], 1 cytomegalovirus (CMV) retinitis [9], 1 HLA B27 uveitis [18], 1 bilateral anterior uveitis [19], 1 serpiginous choroiditis [20], 1 fungal endophthalmitis [21], 1 T/natural killer (NK) lymphoma [22], 1 presumed histoplasmosis [23], and 1 immune recovery uveitis in an AIDS patient after CMV retinitis [24]. …”

Section: Discussionmentioning

confidence: 99%

Spontaneous closure of macular holes secondary to posterior uveitis: case series and a literature review

Bonnin

Cornut

Chaise

et al. 2013

J OPHTH INFLAMM INFECT

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The occurrence of a macular hole due to posterior uveitis is infrequently reported. We report the evolution of three cases of macular holes secondary to posterior segment inflammation. A complete inflammatory and infectious assessment found one case of toxocariasis, one of sarcoidosis, and one of syphilis. After medical etiological treatment, macular hole closure was rapidly obtained in all the cases and confirmed by spectral domain optic coherence tomography, with visual acuity improvement. Fibrous scarring developed in two cases, and foveal photoreceptor complex normalization was observed in the sarcoidosis case. These observations demonstrate that macular holes secondary to posterior uveitis frequently resolve without surgical intervention and so could be underdiagnosed if the patient is not evaluated at the time of onset before spontaneous hole closure.

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“…Halkiadakis and colleagues successfully treated SMH and concomitant active uveitis with periocular triamcinolone [75]. We have similarly closed an SMH which developed after resolution of intermediate uveitis, and persisted after macular hole surgery [76]. CME plays a key role in both causation and recurrence of idiopathic macular hole [7,77].…”

Section: Secondary Macular Holesmentioning

confidence: 96%

Secondary macular holes: when to jump in and when to stay out

Shukla

2013

Expert Review of Ophthalmology

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Pharmacotherapeutic closure of a uveitic macular hole persisting after vitrectomy

Cited by 12 publications

References 6 publications

Rhegmatogenous retinal detachment due to a macular hole in a patient with pars planitis: a case report

Rhegmatogenous retinal detachment due to a macular hole in a patient with pars planitis: a case report

Spontaneous closure of macular holes secondary to posterior uveitis: case series and a literature review

Secondary macular holes: when to jump in and when to stay out

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