The Citrus species from family Rutaceae has worldwide applications such as cardiovascular and gastrointestinal
problems. Phytochemical investigations have shown that these plants have constituents including
flavonoids, limonoids and carotenoids. There are many reports on a wide range of activities such as antiinflammatory,
anti-oxidant, immunomodulatory, metabolic, cardiovascular and neuroprotective effects. In the
current review, we discuss information regarding botany, phytochemistry, ethnobotany uses, traditional
knowledge and pharmacological aspects of the Citrus species.