Pharmacology and Toxicology of 1, 1-Dimethylhydrazine (UDMH)

Back, Kenneth G.; Thomas, Anthony A.

doi:10.1080/00028896309342919

Cited by 24 publications

(12 citation statements)

References 2 publications

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“…It was unclear if the retention was monitored only for the 51-64 min duration of exposure. Back et al (1963) studied the absorption, distribution, and excretion of [C 14 ]-1,1-dimethylhydrazine. Various aspects of the disposition of dimethylhydrazine were measured in monkeys, dogs, cats, rabbits, or rats following intravenous or intraperitoneal administration.…”

Section: Discussionmentioning

confidence: 99%

Dimethylhydrazine

2001

Inhalation Toxicology

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Section: Discussionmentioning

confidence: 99%

Dimethylhydrazine

2001

Inhalation Toxicology

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“…UDMH is miscible in water and will migrate into water sources and can be dangerous for water consumers. The LD 50 of the UDMH in rats is 104 mg kg −1 which suggests that UDMH has a high toxicity [3]. UDMH is an explosive, which is mainly used as a liquid propellant in military applications.…”

Section: Introductionmentioning

confidence: 99%

Mineralization of unsymmetrical dimethylhydrazine (UDMH) via persulfate activated by zero valent iron nano particles: modeling, optimization and cost estimation

Zarei

Rezaei-Vahidian

Soleymani

2015

Desalination and Water Treatment

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2015): Mineralization of unsymmetrical dimethylhydrazine (UDMH) via persulfate activated by zero valent iron nano particles: modeling, optimization and cost estimation, Desalination and Water Treatment, A B S T R A C TThis work examined the mineralization of unsymmetrical dimethylhydrazine (UDMH) as an alarming organic contaminant, via persulfate (PS) oxidation process. Nano zero-valent iron (NZVI) particles, as a source of ferrous ions, were synthesized and used to activate PS ions in the media. The effective operational parameters such as NZVI dosage, pH, and initial amount of PS were optimized by response surface methodology as a statistical experimental design. The mineralization efficiency and the demand-operating cost (DOC) of the process were well modeled by two second-order polynomial equations. Based on the desirability, function optimization of the responses was performed. In the optimum condition of pH 3.45, [PS] 0 = 836.16 mg L −1 , and [NZVI] 0 = 158.45 mg L −1 , the model predicted 91% of the UDMH mineralization and 10 US$/m 3 for the DOC that the electrical energy constitutes 69% of the total cost. Compared with the related literatures about treatment of the UDMH, the applied NZVI/PS process reached a high efficiency using lower chemicals.

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“…The increased use of 1,1-dimethylhydrazine (UDMH) as a missile propellant in recent years has necessitated numerous toxicological and pharmacological studies of this compound to obtain information needed for diagnosis and treatment in the event of accidental UDMH exposure in man (refs 2, 3, 4,16,17,24,25,26,36). These studies have also been useful in setting safe threshold limit values, and in establishing proper propellant handling procedures.…”

Section: Introductionmentioning

confidence: 99%

Pyridoxine (Vitamin B6) Toxicity Literature Review

Schneider¹

1964

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Pharmacology and Toxicology of 1, 1-Dimethylhydrazine (UDMH)

Cited by 24 publications

References 2 publications

Dimethylhydrazine

Dimethylhydrazine

Mineralization of unsymmetrical dimethylhydrazine (UDMH) via persulfate activated by zero valent iron nano particles: modeling, optimization and cost estimation

Pyridoxine (Vitamin B6) Toxicity Literature Review

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