Pharmacological Properties of Matricaria recutita: A Review

Murti, Krishna; Panchal, Mayank; Gajera, Vipul; Solanki, Jinal

doi:10.5567/pharmacologia.2012.348.351

Cited by 29 publications

(18 citation statements)

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“…Similar to terpenes, many of these compounds have also been shown to have anti‐inflammatory, neuroprotective, and anti‐cancer effects . Apigenin has anxiolytic effects, and inhibits TNF‐α which is involved in many inflammatory conditions. Cannflavin A and B have potent anti‐inflammatory effects, with Cannflavin A shown to inhibit PGE‐2 30 times more potently than aspirin .…”

Section: Flavonoidsmentioning

confidence: 99%

Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science

2018

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There is accumulating evidence for various therapeutic benefits of cannabis/cannabinoids, especially in the treatment of pain, which may also apply to the treatment of migraine and headache. There is also supporting evidence that cannabis may assist in opioid detoxification and weaning, thus making it a potential weapon in battling the opioid epidemic. Cannabis science is a rapidly evolving medical sector and industry with increasingly regulated production standards. Further research is anticipated to optimize breeding of strain-specific synergistic ratios of cannabinoids, terpenes, and other phytochemicals for predictable user effects, characteristics, and improved symptom and disease-targeted therapies.

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Section: Flavonoidsmentioning

confidence: 99%

Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science

2018

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“…Essential oil analysis by GC-MS and TLC methods revealed as a main compounds, bisabolol oxide A, bisabolone oxide, bisabolol oxide B, chamazulene, spathulenol and farnesene. Murti et al (2012), besides the mentioned substances, also presented sesquiterpens, apigenin, luteolin, quercetin, umbelliferone and en-yndicycloether as chemical components of chamomile. Also, Euphrasia contains a lot of chemical compounds represented mainly by phenolic compounds (for exexample, chlorogenic, caffeic acids, quercetin-3-Orutinoside (9) and apigenin),organic acids (for example, citric acid , quinic acid , acetic acid ), sterols (cholesterol , β-Sitosterol) and fatty acids (for example, myrystic, palmitic, docosahexaenoic) determined by different chromatographic methods (Teixeira and Silva, 2013).…”

Section: Maximusmentioning

confidence: 99%

Allelopathic effect of popular medicinal plants on Fagopyrum esculentum (Moench), Papaver somniferum (L.) and Brassica napus var. oleifera (L.)

Matysiak¹,

Kaczmarek²,

Kierzek³

2014

J. Med. Plants Res.

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Glasshouse experiments were carried out to assess the effect of popular medicinal herbs dry matter on germination and early growth of common buckwheat (Fagpopyrum esculentum), opium poppy (Papaver somniferum) and two cultivars of oilseed rape (Brassica napus var. oleifera). Depending on species of the herb, leaves, inflorescences, fruits and whole plants were used. The greatest stimulatory effect on seedling emergence of common buckwheat was exhibited by Urtica sp. while seedling emergence of opium poppy was most affected by Hypericum sp. Seedling emergence of common buckwheat was reduced by the use of Matricaria sp. inflorescence, while Euphrasia sp. herb reduced emergence of opium poppy. Urtica sp. leaves caused a significant increase in fresh matter of buckwheat as well as opium poppy. The greatest reduction in fresh matter of buckwheat was noted as a result of using Euphrasia sp. herb, while in the case of opium poppy, fresh matter was most reduced by using Tilia sp. inflorescence. Mentha sp. exhibited a strong stimulatory effect on seedling emergence of oilseed rape cultivar Californium, while Achillea sp. had an inhibitory influence. All the examined medicinal plants inhibited seedling emergence of semi-dwarf hybrid oilseed rape cv. Maximus. Inhibitory or a stimulatory effect on germination of winter oilseed rape seeds was not always correlated with a reduction or an increase in plant fresh matter.

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“…Several species of chamomile are spread over the world, however, the most popular of all is known as German chamomile (Matricaria chamomilla L.) (2,3). M. chamomilla is cultivated in many parts of the world for its historical use in the food and cosmetic products as well as herb infusions for its medicinal benefits (4)(5)(6)(7). In Iran, M. chamomilla is known as Babuna and traditionally is used for the treatment of a number of ailments such as gastrointestinal problems including indigestion, carminative, flatulence, colic and diarrhea (8).…”

Section: Introductionmentioning

confidence: 99%

“…M. chamomilla is also traditionally used for treatment of common cold and fever (5). It is believed that M. chamomilla has analgesic effect and therefore it is used for treatment of painful conditions such as toothache, dysmenorrheal and rheumatism (4). Phytochemical studies identified presence of essential oils, flavonoids and coumarins constituents in the M. chamomilla (10)(11)(12).…”

Section: Introductionmentioning

confidence: 99%

Effect of Matricaria chamomilla hydro-alcoholic and flavonoids rich extracts on rat isolated uterus

Sadraei

Sajjadi

Asghari

et al. 2020

J Herbmed Pharmacol

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Introduction: Pharmacological studies confirm antispasmodic activities of chamomile (Matricaria chamomilla) extract on intestinal smooth muscles and it has been suggested that chamomile increases uterus tone, but so far there is no scientific studies which support this assumption. Therefore, this study was designed to determine spasmodic and spasmolytic activities of M. chamomilla extracts on rat isolated uterus. Methods: Hydro-alcoholic extract of M. chamomilla was prepared by maceration technique. Flavonoids rich extract was prepared by liquid in liquid extraction technique. The spasmodic effects of the extracts were assessed on spontaneously contracting rat uterus. The myorelaxant effect of M. chamomilla extracts was validated on isolated uterus contractions induced by KCl, acetylcholine (ACh), electrical field stimulation (EFS) and oxytocin. Results: Hydro-alcoholic extract of M. chamomilla (0.8 and 1.6 mg/mL) enhanced spontaneous movement of rat isolated uterus smooth muscle suspended in an organ bath. On the other hand, flavonoids rich fraction only diminished uterus contractile activities. Flavonoids rich extract of the plant at bath concentration ranges of 40 μg/mL to 400 μg/mL attenuated uterus response to ACh, KCl, EFS and oxytocin. The hydro-alcoholic extract of M. chamomilla at higher concentration ranges (250 μg/mL to 1.5 mg/mL) inhibited uterus contractions induced by the above spasmogens. Conclusion: The present study confirms both spasmodic and spasmolytic activities M. chamomilla hydro-alcoholic extract. Therefore, medicinal use of the crude extract of M. chamomilla may initiate uterus contraction which could increase risk of spontaneous miscarriage or premature parturition.

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Pharmacological Properties of Matricaria recutita: A Review

Cited by 29 publications

References 1 publication

Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science

Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science

Allelopathic effect of popular medicinal plants on Fagopyrum esculentum (Moench), Papaver somniferum (L.) and Brassica napus var. oleifera (L.)

Effect of Matricaria chamomilla hydro-alcoholic and flavonoids rich extracts on rat isolated uterus

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