1981
DOI: 10.1055/s-2007-971532
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Pharmacological Investigations on Vitexin

Abstract: Vitexin (8--D-glucopyranosyl-apigenm) (VT), isolated from the flowers of Ochrocarpus longifolius L. and Arnebia hispidissima Dc., exhibited potent hypotensive, anti-inflammatory and anti-spasmodic (nonspecific) properties. Hypotensive effect of VT was attributed to its ganglion-blocking properties and antiinflammatory effects to its anti-histaminic, anti-bradykinin and anti-serotonin properties.

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Cited by 83 publications
(43 citation statements)
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“…Vitexin and isovitexin were identified in the AEC with standards. These flavonoids have been described in other plants as the genus Passiflora (Muller et al, 2005), Ochrocarpus and Arnebia (Prabhakar et al, 1981). Only an early report qualitatively described the effects of vitexin in vitro and in vivo as hypotensive, antiinflammatory and antispasmodic (Prabhakar et al, 1981).…”
Section: Discussionmentioning
confidence: 99%
“…Vitexin and isovitexin were identified in the AEC with standards. These flavonoids have been described in other plants as the genus Passiflora (Muller et al, 2005), Ochrocarpus and Arnebia (Prabhakar et al, 1981). Only an early report qualitatively described the effects of vitexin in vitro and in vivo as hypotensive, antiinflammatory and antispasmodic (Prabhakar et al, 1981).…”
Section: Discussionmentioning
confidence: 99%
“…There are many reports indicating biological benefits of these flavonoids and crude extracts of P. Foetida leaves. Vitexin exhibited potent hypotensive, anti-inflammatory and anti-spasmodic properties [15]. Recently vitexin and isovitexin have been shown to effectively inhibit the formation of advanced glycationend products (AGEs) which are found to be implicated in diabetic complications [16].…”
Section: Pharmacological Valuesmentioning
confidence: 99%
“…in guinea pigs and rabbits. This effect is claimed to arise from the ability to block the vegetative ganglia (PRABHAKAR et al 1981).…”
Section: Flavonoidsmentioning
confidence: 99%