Pharmacological Interventions for the Prevention and Treatment of Kidney
Injury Induced by Radiotherapy: Molecular Mechanisms and Clinical
Perspectives
Abstract::
More than half of cancer patients need radiotherapy during the course of their treatment. Despite the beneficial aspects, the destructive effects of radiation beams on normal tissues lead to oxidative stress, inflammation, and cell injury. Kidneys are affected during radiotherapy of abdominal malignancies. Radiation nephropathy eventually leads to the release of factors triggering systemic inflammation. Currently, there is no proven prophylactic or therapeutic intervention for the management of radiation-ind… Show more
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