Pharmacological importance of Kunxian Capsule in clinical applications and its adverse effects: A review

Comparative pharmacokinetics of six components in normal and rheumatoid arthritis rats after intragastrical administration of Qianghuo Shengshi Decoction granules by LC-MS/MS

“…Studies have suggested that various TCM extracts, single herb, and prescriptions exert therapeutic effects on RA primarily by inhibiting the proliferation of abnormal immune cells and inflammatory factors, regulating the immune system, and reducing angiogenesis, etc. ( He et al, 2021 , Ma et al, 2023 , Xie et al, 2021 ). Qianghuo Shengshi Decoction (QSD) has clear anti-inflammatory and analgesic effects on the organism by regulating the expression of the mitogen-activated protein kinases (MAPKs) / cAMP response element-binding protein (CREB) signaling pathway ( Hu et al, 2022 ), and QSD has been widely used to treat a variety of inflammatory and pain diseases, including RA ( Dong et al, 2018 ).…”