Pharmacological effects and target analysis of Guipi wan in the treatment of cerebral ischemia-reperfusion injury
Jianfeng Zhang,
Li Luo,
Yanyan Guo
et al.
Abstract:Guipi wan (GPW) is a traditional Chinese medicine commonly used in clinical practice, typically to treat neurological diseases such as neurasthenia and traumatic brain injury. It may have positive effects on cerebral ischemia‒reperfusion injury (cI/R). This study aimed to assess the effects of GPW in a mouse model of cI/R and find its possible targets. C57BL/6J mice were used to establish the cI/R model, and the laser speckle doppler was used to determine the success of the model. GPW was administered intragas… Show more
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