Pharmacological effect of T-NilPlus® and Synertox®, commercial anti-mycotoxins, on broiler chickens in Egypt

Abstract

The present study was carried out to investigate the potential ameliorative effect of two commercial anti-mycotoxins, containing Saccharomyces cerevisiae cell wall as prebiotic (T-Nil Plus®) and Bacillus subtilis as probiotic (Synertox®) on performance and some biochemical parameters of broilers. One hundred and twenty chicks one day old chicks were divided into 3 equal groups. 1st group was served as control, 2nd group was given T-Nil Plus®. The 3rd group was given Synertox®. Chicken’s performance was estimated. Serum samples obtained from each group for biochemical analysis. Tissues samples were collected for histopathological examination. The obtained results revealed that, T-Nil plus® induced a marked reduction in body weight gain and an elevation in Feed consumption, moreover, a marked elevation in, alanine aminotransferase (ALT), creatinine and malondialdehyde (MDA) and a marked reduction in aspartate aminotransferase (AST) was detected. While Synertox® caused a significant decrease in body weight, body weight gain and no change in feed conversion rate (FCR) and a marked elevation in ALT, creatinine and a marked reduction in AST and nitric oxide (NO) and it caused a significant reduction in serum glucose level of the birds. In conclusion, Synertox® induced a powerful effect comparing to T-Nil Plus®, as it induces a good FCR and increases the response of the birds against oxidative stress.

Ameliorative Effect of Syner-Tox and Nigella Sativa on Growth Performance and Some Serum Biochemical Parameters in Broiler Chicks Fed Diets Contaminated With Aflatoxins

“…ST was manufactured by IFT Animal Health (Cairo, Egypt). Birds received ST at a dose of 0.5 ml/L in drinking water (Amer et al, 2022). G4: Administered ration contaminated by aflatoxin (300 ppb) plus Nigella sativa (10 gm/kg feed).…”