Pharmacological assessment of the antineoplastic and immunomodulatory properties of a new spiroindolone derivative (7’,8’-Dimethoxy-1’,3’-dimethyl-1,2,3’,4’-tetrahydrospiro[indole-3,5’-pyrazolo[3,4-c]isoquinolin]-2-one) in chronic myeloid leukemia

Alves, Carlos Eduardo de Castro; Bogza, S. L.; Bohdan, Nathalie; Rozhenko, Alexander; Gomes, Alice de Freitas; Oliveira, Regiane Costa de; Azevedo, Renata Galvão de; Maciel, Larissa G.; Dhyani, Anamika; Grafov, Andriy; Pontes, Gemilson Soares

doi:10.1007/s10637-023-01382-3

Invest New Drugs

2023

DOI: 10.1007/s10637-023-01382-3

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Pharmacological assessment of the antineoplastic and immunomodulatory properties of a new spiroindolone derivative (7’,8’-Dimethoxy-1’,3’-dimethyl-1,2,3’,4’-tetrahydrospiro[indole-3,5’-pyrazolo[3,4-c]isoquinolin]-2-one) in chronic myeloid leukemia

Carlos Eduardo de Castro Alves

S. L. Bogza

Nathalie Bohdan

et al.

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Pharmacological assessment of the antineoplastic and immunomodulatory properties of a new spiroindolone derivative (7’,8’-Dimethoxy-1’,3’-dimethyl-1,2,3’,4’-tetrahydrospiro[indole-3,5’-pyrazolo[3,4-c]isoquinolin]-2-one) in chronic myeloid leukemia

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