Pharmacological activities of water extracts ofUmbelliferae plants

“…(Umbelliferae) have been used in the traditional Chinese medicine since ancient times as an antipyretic and analgesic to treat colds, headaches, and toothaches. They have been reported to protect against dexamethasone-induced disorders and to possess hepatoprotective, anti-inflammatory, antimutagenic [8], antimicrobial [9], antitumor [10], free radical-scavenging [11], and skin-whitening [12] activities. They are known to contain a large number of coumarins and furanocoumarins [13].…”

mentioning

confidence: 99%

Chemical Composition and Antioxidant Activities of Different Polysaccharides from the Roots of Angelica dahurica

et al. 2011

Chemistry & Biodiversity

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The total crude polysaccharides (CADPs), isolated from the roots of Angelica dahurica by H(2) O extraction, EtOH precipitation, and dialysis, and the four fractions ADP1, ADP2, ADP3, and ADP4, obtained by gel filtration of the CADPs, were analyzed to characterize their composition and evaluated for their antioxidant activity using different in vitro tests such as the malondialdehyde (MDA)-production, the ferrous ion (Fe(2+) )-chelating, and the HO(.) radical-scavenging assays. The predominant neutral monosaccharides in the four fractions were identified as arabinose, galactose, and glucose, while the composition and ratio of the monosaccharides were different between the fractions. The CADPs and its fractions were found to significantly inhibit lipid peroxidation, chelate Fe(2+) , and scavenge HO(.) radicals, indicating that these polysaccharides possessed antioxidant activity. Among the four fractions, ADP4 exhibited the strongest antioxidant activity, which was stronger than that of the control antioxidant vitamin E (Vit E). Taken together, the chemical composition of these polysaccharides might affect their antioxidant activity, and ADP4 could be explored as a source of potential novel natural antioxidants for food and pharmaceutical purposes.

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“…(Umbelliferae), is an important herbal medicine (Perry, 1980;Hsu et al, 1986) which is listed in the Chinese Pharmacopoeia, is used as an antipyretic and analgesic for cold, headaches and toothaches (Tang and Eisenbrand, 1992). It is reported to protect against dexamethasone-induced disorders, and also to possess liver protective activity, antimicrobial activity, anti-inflammatory activity, and antimutagenic activity (Kim et al, 1991). Angelica dahuricae is known to contain a large number of coumarins and furanocoumarins, e.g., coumarin, scopoletin, psoralen, xanthotoxin, bergapten, and imperatorin (Saiki et al, 1971).…”

Section: Introductionmentioning

confidence: 98%