Pharmacological Activities of Natural Products from Marine Seaweed Turbinaria ornata: A Review

Renuka, Remya Rajan; Julius, Angeline; Ramadoss, Ramya; Parthiban, S.; Bharath, N.; Pavana, B.; Samrot, Antony V.; Kanwal, Smita; Mohanavel, V.; Gemeda, Firomsa Wakjira

doi:10.1155/2022/4784608

Cited by 4 publications

(2 citation statements)

References 61 publications

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“…T. ornata also displayed anti-proliferative actions, as well as several biological characteristics (cytotoxic, antimicrobial, pesticide, etc.) [ 39 ]. The current study is the first to describe the pesticidal activity of several extracts, and their fractions demonstrated insecticidal activity.…”

Section: Discussionmentioning

confidence: 99%

Insecticidal Activity of Tannins from Selected Brown Macroalgae against the Cotton Leafhopper Amrasca devastans

Petchidurai,

Sahayaraj,

Al-Shuraym

et al. 2023

Plants

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Seaweeds, also known as marine macroalgae, are renewable biological resources that are found worldwide and possess a wide variety of secondary metabolites, including tannins. Drifted brown seaweed (DBSW) is particularly rich in tannins and is regarded as biological trash. The cotton leaf hopper Amrasca devastans (Distant) has caused both quantitative and qualitative losses in cotton production. Drifted brown seaweeds (DBSWs) were used in this study to extract, qualitatively profile, and quantify the levels of total tannins, condensed tannins, hydrolyzable tannins, and phlorotannins in the seaweeds; test their insecticidal activity; and determine the mechanism of action. The largest amount of tannin extract was found in Sargassum wightii Greville (20.62%) using the Soxhlet method (SM). Significantly higher amounts of hydrolyzable tannins (p = 0.005), soluble phlorotannins (p = 0.005), total tannins in the SM (p = 0.003), and total tannins in the cold percolation method (p = 0.005) were recorded in S. wightii. However, high levels of condensed tannins (CTAs) were observed in Turbinaria ornata (Turner) J. Agardh (p = 0.004). A. devastans nymphs and adults were examined for oral toxicity (OT) and contact toxicity (CT) against DBSW tannin crude extract and column chromatographic fractions 1 (Rf = 0.86) and 2 (Rf = 0.88). Stoechospermum polypodioides (J.V. Lamouroux) J. Agardh crude tannin was highly effective against A. devastans using the OT method (LC50, 0.044%) when compared with the standard gallic acid (LC50, 0.044%) and tannic acid (LC50, 0.122%). Similarly, S. wightii fraction 2 (LC50, 0.007%) showed a greater insecticidal effect against A. devastans adults in OT than gallic acid (LC50, 0.034%) and tannic acid (LC50, 0.022%). The mechanism of action results show that A. devastans adults treated with crude tannin of T. ornata had significantly decreased amylase, protease (p = 0.005), and invertase (p = 0.003) levels when compared with the detoxification enzymes. The levels of glycosidase, lactate dehydrogenase, esterase, lipase, invertase, and acid phosphate activities (p = 0.005) of S. wightii were reduced when compared with those of the Vijayneem and chemical pesticide Monocrotophos. In adult insects treated with LC50 concentrations of S. wightii tannin fraction 1, the total body protein (9.00 µg/µL) was significantly reduced (OT, LC50—0.019%). The SDS-PAGE analysis results also show that S. wightii tannin fraction 1 (OT and CT), fraction 2 (OT), and S. polypodioides fraction 2 (CT) had a significant effect on the total body portion level, appearance, and disappearance of some proteins and polypeptides. This study shows that the selected brown macroalgae can be utilized for the safer management of cotton leaf hoppers.

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Section: Discussionmentioning

confidence: 99%

Insecticidal Activity of Tannins from Selected Brown Macroalgae against the Cotton Leafhopper Amrasca devastans

Petchidurai,

Sahayaraj,

Al-Shuraym

et al. 2023

Plants

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“…Turbinaria ornata ( T. ornata ) is a brown alga that belongs to the Sargassaceae family, of the class Phaeophyceae and is found in tropical and subtropical regions of the Western and Central Pacific, as well as the Indian Ocean. They occur in small clusters closely related to the fissures of basalt rocks in high wave action regions, apart from the fissures of coral heads at 20–30 m. This alga’s morphological characteristics enable it to survive in challenging ecological conditions ( Remya et al, 2022 ). T. ornata is rich in bioactive compounds including saponins, fucoxanthin, terpene flavonoids, phenols, proteins, sulfates, polysaccharides, fucosterol, polyphenols, and alkaloids ( Deepak et al, 2017 ).…”

Section: Introductionmentioning

confidence: 99%

Structural characterization, antioxidant and anti-uropathogenic potential of biogenic silver nanoparticles using brown seaweed Turbinaria ornata

Raj,

Muthukumar,

Dahms

et al. 2023

Front. Microbiol.

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Alternative treatment strategies for urinary tract infections (UTIs) are becoming more necessary due to increasing drug resistance patterns in uropathogens. Nanoparticle-based therapeutics is emerging as a way to treat UTIs. In the present study, using Turbinaria ornata extract, silver nanoparticles (AgNPs) were synthesized, characterized, and their anti-uropathogenic activity was evaluated. The stability and formation of synthesized To-AgNPs were confirmed by UV-visible spectroscopy, FTIR, XRD, SEM, and DLS. An FTIR spectrum confirmed the presence of seaweed functional groups in To-AgNPs, a XRD analysis confirmed their crystalline nature, and SEM imaging confirmed their spherical nature with an average size of 73.98 nm with diameters ranging from 64.67 to 81.28 nm. This was confirmed by TEM results. DLS determined that the cumulant hydrodynamic diameter of To-AgNPs was 128.3 nm with a PdI of 0.313 and the zeta potential value were found to be –63.3 mV which indicates the To-AgNPs are negatively charged and more stable. DPPH assays were used to assess the antioxidant activity of biosynthesized To-AgNPs, while an agar well diffusion method was used to test the antibacterial activity against uropathogens, including Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecalis, and Klebsiella pneumoniae. The To-AgNPs showed the highest susceptibility to S. aureus (15.75 ± 0.35 mm) and E. coli (15 ± 0.7 mm) with MIC values of 0.0625 and 0.125 mg/ml, respectively in macro broth dilution method and observed considerable membrane damage under CLSM and SEM. To-AgNPs displayed stronger antioxidant and antimicrobial activity, suggesting they may be developed as a new class of antimicrobial agents for treating UTIs.

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Nanotechnology and Nature-Sourced Ingredients for Tackling Neurodegenerative Diseases

Rocha,

Ribeiro,

Machado

et al. 2023

Theranostic Applications of Nanotechnology in Neurological Disorders

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Pharmacological Activities of Natural Products from Marine Seaweed Turbinaria ornata: A Review

Cited by 4 publications

References 61 publications

Insecticidal Activity of Tannins from Selected Brown Macroalgae against the Cotton Leafhopper Amrasca devastans

Insecticidal Activity of Tannins from Selected Brown Macroalgae against the Cotton Leafhopper Amrasca devastans

Structural characterization, antioxidant and anti-uropathogenic potential of biogenic silver nanoparticles using brown seaweed Turbinaria ornata

Nanotechnology and Nature-Sourced Ingredients for Tackling Neurodegenerative Diseases

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