Pharmacokinetic Profile of a Drug Repurposing Candidate for the Treatment of Cutaneous Leishmaniasis (in Silico)
Arlindo Gonzaga Branco Junior,
Nilton Fagner de Oliveira Araújo,
Saara Neri Fialho
et al.
Abstract:The calculated or experimental physical-chemical Properties are important for choosing substances that will be used in the treatment of several diseases by different administration routes. Chloroquine, for example, is a drug with several biological activities that has been constantly investigated as an alternative to drug repurposing in different diseases. With respect to leishmaniasis, there are few treatment options, which are invasive and have several adverse effects. Another point is the identification of … Show more
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