Expert Opinion on Drug Metabolism & Toxicology

2022

DOI: 10.1080/17425255.2022.2117606

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Pharmacokinetic considerations surrounding the use of levetiracetam for seizure prophylaxis in neurocritical care – an overview

Gianluca D’Onofrio

¹

,

²

,

Elisabetta Amadori

³

et al.

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Cited by 4 publications

(1 citation statement)

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“…LEV and brivaracetam (BRV) primarily act by binding SV2A [ 58 ]. LEV is a broad-spectrum ASM, that is effective in both focal and primary generalized seizures [ 58 ]. Its partial effectiveness on absences has been described in Section 3.2.2 .…”

Section: Mechanisms Of Actionmentioning

confidence: 99%

Pharmacodynamic rationale for the choice of antiseizure medications in the paediatric population

D'Onofrio,

Roberti,

Riva

et al. 2024

Neurotherapeutics

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No abstract

“…LEV and brivaracetam (BRV) primarily act by binding SV2A [ 58 ]. LEV is a broad-spectrum ASM, that is effective in both focal and primary generalized seizures [ 58 ]. Its partial effectiveness on absences has been described in Section 3.2.2 .…”

Section: Mechanisms Of Actionmentioning

confidence: 99%

Pharmacodynamic rationale for the choice of antiseizure medications in the paediatric population

D'Onofrio,

Roberti,

Riva

et al. 2024

Neurotherapeutics

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No abstract

Basics of neurosciences [anatomy, physiology and pharmacology]

Gupta,

Mukhi,

Singhal

2024

Neurological and Neurosurgical Emergencies

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No abstract

Comparison of the efficacy and safety of sodium valproate versus levetiracetam in the treatment of severe traumatic brain injury

Huang,

Lin,

Wang

et al. 2024

International Journal of Neuroscience

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No abstract

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