Pharmacokinetic analysis of orally administered puerarin in human saliva using an indirect competition ELISA

Qu, Huihua; Feng, Wan Yong; Shan, Wenchao; Wang, Xueqian; Cheng, Jinjun; Kong, Hui; Zhao, Yan; Wang, Qingguo

doi:10.1039/c5ay01132a

Cited by 5 publications

(1 citation statement)

References 28 publications

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“…Huihua et al developed a quick, specific, and sensitive ELISA to determine puerarin in human saliva by adding anti-puerarin MAbs to the reaction, and further applied this ELISA to the pharmacokinetic analysis of puerarin from healthy volunteers following oral administration of different doses of pueraria capsules [ 65 ]. In another investigation, the established ELISA method for geniposide detection was applied for assessment of biological samples from mice and pharmacokinetics of geniposide in mice after oral administration of Huanglian-Jiedu-Tang (a traditional Chinese medicine prescription) of three dosages [ 15 ].…”

Section: Immunoassay For Mpnp Using Mabsmentioning

confidence: 99%

Monoclonal Antibodies and Immunoassay for Medical Plant-Derived Natural Products: A Review

et al. 2017

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Owing to the widespread application value, monoclonal antibodies (MAbs) have become a tool of increasing importance in modern bioscience research since their emergence. Recently, some researchers have focused on the production of MAbs against medical plant-derived natural products (MPNP), the secondary metabolites of medical plants. At the same time, various immunoassay methods were established on the basis of these MPNP MAbs, and then rapidly developed into a novel technique for medical plant and phytomedicine research in the area of quality control, pharmacological analysis, drug discovery, and so on. Dependent on the research works carried out in recent years, this paper aims to provide a comprehensive review of MAbs against MPNP and the application of various immunoassay methods established on the basis of these MAbs, and conclude with a short section on future prospects and research trends in this area.

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Section: Immunoassay For Mpnp Using Mabsmentioning

confidence: 99%

Monoclonal Antibodies and Immunoassay for Medical Plant-Derived Natural Products: A Review

et al. 2017

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Distribution kinetics of puerarin in rat hippocampus after acute local cerebral ischemia

Kong

Zhang

Cheng

et al. 2019

Journal of Pharmaceutical and Biomedical Analysis

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A novel electrochemical sensor based on WO3 nanorods-decorated poly(sodium 4-styrenesulfonate) functionalized graphene nanocomposite modified electrode for detecting of puerarin

Jing

Zheng

Zhao

et al. 2017

Talanta

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Pharmacokinetic analysis of orally administered puerarin in human saliva using an indirect competition ELISA

Abstract: The pharmacokinetics of puerarin in human saliva following oral administration of pueraria capsules were successfully studied by an icELISA method.

Cited by 5 publications

References 28 publications

Monoclonal Antibodies and Immunoassay for Medical Plant-Derived Natural Products: A Review

Monoclonal Antibodies and Immunoassay for Medical Plant-Derived Natural Products: A Review

Distribution kinetics of puerarin in rat hippocampus after acute local cerebral ischemia

A novel electrochemical sensor based on WO3 nanorods-decorated poly(sodium 4-styrenesulfonate) functionalized graphene nanocomposite modified electrode for detecting of puerarin

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