Pharmacoinvasive Approach to the Treatment of Acute ST‐Segment Elevation Myocardial Infarction. Current State of the Problem

Milenkina, Sofia; Belogurov, A. A.; Delver, E. P.; Staroverov, I I

doi:10.18087/cardio.2020.1.n699

Cited by 2 publications

(2 citation statements)

References 35 publications

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“…Прямое сравнение влияния ЧКВ с тромболизисом на риск развития осложнений ИМ не проводилось, а большинство крупных исследований, в которых сравнивали между собой ЧКВ с фармакоинвазивной стратегией, не включали риск развития СН или КШ в качестве отдельной конечной точки. С другой стороны, показано, что СН регистрируется реже при сочетании тромболизиса с последующей ЧКВ по сравнению с первичной ЧКВ, однако в случае фармакоинвазивной стратегии повышается риск развития геморрагического инсульта [27]. Риск развития КШ также ниже при сочетании тромболизиса и ЧКВ при невозможности раннего выполнения последнего по сравнению с первичным ЧКВ.…”

Section: основные осложнения инфаркта миокарда влияние реперфузии на ...unclassified

Treatment of Patients with Myocardial Infarction in Modern Conditions of a Regional Vascular Center

Kuzmina¹,

Muradyan²,

Parkhomenko³

2022

Neotložnaâ med. pomoŝʹ

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The article highlights the problem of providing care for patients with acute coronary syndrome, given the high myocardial infarction (mi) morbidity and mortality among the youth population. The main method of managing acute myocardial infarction is reperfusion therapy, performing revascularization with percutaneous coronary intervention (pci) in the shortest possible time from the disease onset. Only rational and timely treatment can reduce mortality after mi, the frequency of its complications, as well the period of inpatient treatment and disability of the population.

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Section: основные осложнения инфаркта миокарда влияние реперфузии на ...unclassified

Treatment of Patients with Myocardial Infarction in Modern Conditions of a Regional Vascular Center

Kuzmina¹,

Muradyan²,

Parkhomenko³

2022

Neotložnaâ med. pomoŝʹ

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“…Однако первостепенное значение при оказании помощи пациентам с ИМпST имеет именно время до восстановления кровотока в инфарктсвязанной артерии. Максимально раннее восстановление кровоснабжения миокарда при остром инфаркте приводит к ограничению зоны повреждения, снижению риска осложнений заболевания, улучшению прогноза [4].…”

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Features of the Reperfusion Therapy for ST-Segment Elevation Myocardial Infarction According to the Russian Registry of Acute Myocardial Infarction – REGION-IM

Boytsov,

Shakhnovich,

Tereschenko

et al. 2024

Kardiologiia

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Aim. Based on data from the Russian REGION-IM registry, to study the features of reperfusion therapy in patients with ST-segment elevation myocardial infarction (STEMI) in real-life clinical practice.Material and methods. REGION-IM is a multicenter prospective observational study. The observational period is divided into 3 stages: during the stay in the hospital and at 6 and 12 months after inclusion in the registry. The patient's records contain demographic and history data; information about the present case of MI, including the time of the first symptom onset, first contact with medical personnel, and admission to the hospital; coronary angiography (CAG) data, percutaneous coronary intervention (PCI) data, and information about the thrombolytic therapy (TLT).Results. Reperfusion therapy was performed in 88.9 % of patients with STEMI. Primary PCI (pPCI) was performed in 60.6 % of patients. The median time from the onset of symptoms to pPCI was 315 minutes [195; 720]. The median time from ECG to pPCI was 110 minutes [84;150]. Isolated TLT was performed in 7.4 %, pharmaco-invasive treatment tactics were used only in 20.9 % of cases. The median time from ECG to TLT (prehospital and in-hospital) was 30 minutes [10; 59], whereas the median time from ECG to prehospital TLT was 18 minutes [10; 39], and in 63 % of patients, TLT was performed more than 10 minutes after diagnosis. PCI followed TLT in 73 % of patients.Conclusion. The frequency of reperfusion therapy for STEMI in the Russian Federation has increased considerably in recent years. The high frequency of pPCI is noteworthy, but the timing of pPCI does not always comply with clinical guidelines. The results of this registry confirm the high demand for pharmaco-invasive strategies in real-life clinical practice. Taking into account geographical and logistical features, implementing timely myocardial reperfusion requires prehospital TLT. However, the TLT frequency in the Russian Federation is still insufficient despite its proven maximum effectiveness in the shortest possible time from the detection of acute MI.

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Pharmacoinvasive Approach to the Treatment of Acute ST‐Segment Elevation Myocardial Infarction. Current State of the Problem

Cited by 2 publications

References 35 publications

Treatment of Patients with Myocardial Infarction in Modern Conditions of a Regional Vascular Center

Treatment of Patients with Myocardial Infarction in Modern Conditions of a Regional Vascular Center

Features of the Reperfusion Therapy for ST-Segment Elevation Myocardial Infarction According to the Russian Registry of Acute Myocardial Infarction – REGION-IM

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