Abstract:Pharmacogenomics has been at the forefront of precision medicine during the last few decades. Precision medicine carries the potential of improving health outcomes at both the individual as well as population levels. To harness the benefits of its initiatives, careful dissection of existing health disparities as they relate to precision medicine is of paramount importance. Attempting to address the existing disparities at the early stages of design and implementation of these efforts is the only guarantee of a… Show more
“…SNP analysis and pharmacogenetic‐based opiate prescribing offers a much more precise and biologically driven approach which could reduce the racial and ethnic bias in opiate prescribing practices 12‐16 . Evidence of the impact of different SNP's in opiate drug response is growing.…”
“…SNP analysis and pharmacogenetic‐based opiate prescribing offers a much more precise and biologically driven approach which could reduce the racial and ethnic bias in opiate prescribing practices 12‐16 . Evidence of the impact of different SNP's in opiate drug response is growing.…”
“…In pharmacogenomics, the study of how individual genetic variations influence drug responses has led to personalized drug prescriptions, minimizing adverse drug reactions, and improving treatment efficacy. Existing health disparities, as they intersect pharmacogenomic research and implementation, are being identified [ 21 ].…”
Section: Precision Medicine and Public Healthmentioning
This paper presents a comprehensive development plan for advancing precision medicine in the autonomous province of South Tyrol, Italy, a region characterized by its bilingual population and unique healthcare challenges. This study highlights the need to address the shortage of healthcare professionals proficient in language for person-centered medicine, the lag in healthcare sector digitalization, and the absence of a local medical university, all within the context of an initiated pharmacogenomics program and a population-based precision medicine study known as the “Cooperative Health Research in South Tyrol” (CHRIS) study. The key strategies for addressing these challenges and integrating CHRIS study findings into a broader precision medicine development plan are discussed, including workforce development and training, investment in digital infrastructure, enhanced data management and analytic capabilities, collaboration with external academic and research institutions, education and capacity building, securing funding and resources, and promoting a patient-centered approach. This study emphasizes the potential benefits of implementing such a comprehensive development plan, including improved early detection, personal ized treatment, and prevention of chronic diseases, ultimately leading to better healthcare outcomes and overall well-being in the South Tyrolean population.
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