Abstract:Objectives
Development of the secondary to ACEI cough leads to discontinuation of the drugs of this group. Assessing the safety of the ACEIs with further development of customized approaches for their administration is a major scientific and practical problem. The objective of this study was to assess the association of the genetic markers with the development of the adverse drug reaction in the form of secondary to enalapril dry cough in the patients with essential arterial hypertension.
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The article presents the concept of development of research in the field of pharmacogenetics and personalized medicine in the Russian Federation and ways of introducing “omics” technologies into widespread clinical practice.
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