Pharmacoepidemiological Research Data Sources in the Nordic Countries—Administrative Registers in Finland, Sweden, and Norway

Prami, Tuire; Juuti, Rosa; Iso-Mustajärvi, Ilona

doi:10.1007/978-3-030-51455-6_6

Cited by 4 publications

(5 citation statements)

References 24 publications

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“…Finland did not have a CF-specific patient registry when this study was conducted. However, in Finland, as in other Nordic countries, legislation allows the use of data from various national healthcare registries for research purposes [ 13 ]. These national registries are collected primarily for administrative purposes, but allow linkage of demographic, diagnostic and healthcare utilization data for scientific purposes.…”

Section: Introductionmentioning

confidence: 99%

Cystic fibrosis patient characteristics and healthcare resource utilization in Finland using linked registries

Malmivaara,

Pölkki,

Prami

et al. 2024

Heliyon

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Section: Introductionmentioning

confidence: 99%

Cystic fibrosis patient characteristics and healthcare resource utilization in Finland using linked registries

Malmivaara,

Pölkki,

Prami

et al. 2024

Heliyon

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“…Moreover, requiring a certain dose is frequent in North American studies, where days' supply is a common variable in claims‐based data 7 . However, in Nordic prescription registers, dose‐related data are only included as a free text‐based variable and is thus uncommonly used 23 …”

Section: Introductionmentioning

confidence: 99%

“…7 However, in Nordic prescription registers, dose-related data are only included as a free text-based variable and is thus uncommonly used. 23 Three large systematic reviews from recent years have assessed the long-term opioid use definitions utilized in previous research, coming to similar recommendations for future studies: (1) a cut-off point of >90 days is preferred to define long-term opioid use, (2) consistency of the use should be assessed and (3) sensitivity analyses assessing these definitions should be applied. 5,7,8 Primarily, we aimed to create a methodology to apply these recommendations to a Nordic setting.…”

Section: Introductionmentioning

confidence: 99%

Describing long‐term opioid use utilizing Nordic prescription registers—A Norwegian example

Hamina

Hjellvik

Handal

et al. 2022

Basic Clin Pharma Tox

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Previous studies have de ned long-term opioid use in varying ways, decreasing comparability, reproducibility and clinical applicability of the research. Based on recent systematic reviews, we aimed to estimate long-term opioid use de ned as use persisting more than three months using one of the Nordic prescription registers. We used the Norwegian Prescription Register (NorPD) to extract data on all opioid dispensations between January 1st 2004 and October 31st 2019. New users of opioids (washout 365 days) were de ned as long-term users if they lled two criteria: 1) they had ≥2 dispensations of opioids, 91-180 days apart; 2) days 0-90 included ≥90 dispensed administration units (e.g., tablets) of opioids. Overall, there were 2,543,224 new users of opioids during the study period. Of these, 354,666 (13.9%) lled the criteria for long-term opioid use at least once. Compared to those who did not ll the criteria (short-term users), long-term users were older, more likely women, and used tramadol, oxycodone, and buprenorphine more frequently as their rst opioid. In conclusion, we found that 1/7 of opioid users continued use longer than 3 months. Future outcome research should identify the clinically most important dose requirements for long-term opioid use criteria.

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“…7 However, in Nordic prescription registers, dose-related data are only included as a free text-based variable and is thus uncommonly used. 23 Three large systematic reviews from recent years have assessed the long-term opioid use de nitions utilized in previous research, coming to similar recommendations for future studies: 1) a cut-off point of >90 days is preferred to de ne long-term opioid use, 2) consistency of the use should be assessed, and 3) sensitivity analyses assessing these de nitions should be applied. 5,7,8 Primarily, we aimed to create methodology to apply these recommendations to a Nordic setting.…”

Section: Introductionmentioning

confidence: 99%

Describing long-term opioid use utilizing Nordic Prescription Registers – A Norwegian example

Hamina

Hjellvik

Handal

et al. 2022

Preprint

View full text Add to dashboard Cite

Previous studies have defined long-term opioid use in varying ways, decreasing comparability, reproducibility, and clinical applicability of the research. Based on recommendations from recent systematic reviews, we aimed to develop methodology to estimate the prevalence of use persisting more than three months utilizing one of the Nordic prescription registers. We used the Norwegian Prescription Register (NorPD) to extract data on all opioid dispensations between January 1st, 2004, and October 31st, 2019. New users of opioids (washout 365 days) were defined as long-term users if they filled two criteria: 1) they had ≥2 dispensations of opioids, 91-180 days apart; 2) days 0-90 included ≥90 dispensed administration units (e.g., tablets) of opioids. Overall, there were 2,543,224 new users of opioids during the study period. Of these, 354,666 (13.9%) filled the criteria for long-term opioid use at least once. Compared to those who did not fill the criteria (short-term users), long-term users were older, more likely women, and used tramadol, oxycodone, and buprenorphine more frequently as their first opioid. In conclusion, we found that 1/7 of opioid users continued use longer than 3 months. Future outcome research should identify the clinically most important dose requirements for long-term opioid use criteria.

show abstract

Pharmacoepidemiological Research Data Sources in the Nordic Countries—Administrative Registers in Finland, Sweden, and Norway

Cited by 4 publications

References 24 publications

Cystic fibrosis patient characteristics and healthcare resource utilization in Finland using linked registries

Cystic fibrosis patient characteristics and healthcare resource utilization in Finland using linked registries

Describing long‐term opioid use utilizing Nordic prescription registers—A Norwegian example

Describing long-term opioid use utilizing Nordic Prescription Registers – A Norwegian example

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