Pharmacist involvement to improve patient outcomes in lower gastrointestinal surgery: a prospective before and after study

Bansal, Neetu; Morris, Jonathan

doi:10.1007/s11096-019-00888-2

Cited by 10 publications

(20 citation statements)

References 17 publications

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“…These DAAs include nucleotide nonstructural (NS) 3/4A protease inhibitors, NS5B polymerase inhibitors, and NS5A polymerase inhibitors. Most of the DAAs are used to treat more than one HCV GT, and all have proven effective and well-tolerated in clinical studies ( Bansal and Morris, 2019 ).…”

Section: Introductionmentioning

confidence: 99%

The effectiveness and safety of direct-acting antivirals for hepatitis C virus treatment: A single-center experience in Saudi Arabia

Alarfaj

Alzahrani

Alotaibi

et al. 2022

Saudi Pharmaceutical Journal

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Section: Introductionmentioning

confidence: 99%

The effectiveness and safety of direct-acting antivirals for hepatitis C virus treatment: A single-center experience in Saudi Arabia

Alarfaj

Alzahrani

Alotaibi

et al. 2022

Saudi Pharmaceutical Journal

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“…35 The involvement of pharmacists may be promising to improve patient outcomes and speed up patient recovery after surgery. 27,28 In this study, we demonstrated that the CPGT effectively improved PONV for pa- 36 feedback, 36 educational outreach 24,37 and dedicated support. 24 Another strength was the enrolment of a series of patient-related outcomes.…”

Section: F I G U R Ementioning

confidence: 59%

“…25 A multidisciplinary clinical pharmacist-led guidance team (CPGT) has gradually been proven as a promising service mode to enhance healthcare quality in previous studies conducted in the First Affiliated Hospital of Zhejiang University (FAHZJ) 19,25,26 and other settings. 27,28 Through active intervention, the CPGT in the FAHZJ has achieved several improvements, such as increasing the rationality of using prophylactic antibiotics in intervention procedures, 26 enhancing the efficacy of cancer pain therapy, and improving postoperative pain of transarterial chemoembolization in patients with hepatocellular carcinoma. 29 In 2015, the enhanced recovery pathway was introduced in the FAHZJ to improve outcomes for surgical patients.…”

Section: What Is K Nown and Objec Tivementioning

confidence: 99%

Pharmacist‐driven multidisciplinary initiative continuously improves postoperative nausea and vomiting in female patients undergoing abdominal surgery

et al. 2020

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What is known and objective The incorrect or insufficient prophylaxis of postoperative nausea and vomiting (PONV) is common in practice. A clinical pharmacist‐led guidance team (CPGT) was established and included in general surgery teams. Objective This study aimed to evaluate the effects of the CPGT on the improvement of PONV and prophylaxis administration. Methods A prospective before‐after study was conducted on 156 female patients undergoing abdominal surgery at a Chinese tertiary teaching hospital from December 2016 to December 2017. A total of 82 patients were enrolled in the preintervention period, and 74 patients were included in the post‐intervention period. The CPGT established the evidence‐based criteria for prophylactic anti‐emetic administration and conducted interventions, including a review of medical records, provision of feedback, educational outreach, and dedicated support. Primary outcomes included the incidence of PONV within 24 hours of surgery, administered number of prophylactic anti‐emetics, and accuracy of the timing for prophylactic anti‐emetics. Outcomes were analysed by logistic regression or multivariable linear regression. Results and discussion After intervention, patients reported significantly less PONV (33.78% vs 56.10%; odds ratio [OR]: 0.29; numbers needed to treat [NNT]: 3.47), vomiting (29.73% vs 45.12%; OR: 0.42; NNT: 5.16) and nausea (31.08% vs 56.10%; OR: 0.24; NNT: 3.19) within 24 hours of surgery. The accuracy of the timing for prophylactic anti‐emetics significantly increased (OR: 3.66; P: .003). Anaesthesiologists administered increased numbers of prophylactic anti‐emetics (OR: 5.82; P < .001). The improvement of PONV did not decrease during the four‐month period after intervention (P: .639). What is new and conclusion The CPGT is a valuable service model to continuously improve PONV and optimize prophylaxis administration.

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“…Institutions have implemented DTP-related process and practice changes at key times in the admission process, that is, six to eight weeks preoperatively (prehospital) to detect and manage anemia, hyperglycemia, and smoking [ 21 ], in the preadmission clinic [ 22 , 23 , 24 ], on admission during medication reconciliation [ 25 , 26 , 27 , 28 ], throughout hospital stay [ 29 , 30 ], and at discharge [ 31 , 32 ]. In addition, theater and ward-based activities to rationalize drug therapy [ 33 , 34 ] include identifying and avoiding or minimizing the use of potentially inappropriate medications for at-risk patient populations: (1) the American Geriatric Society’s (AGS) Beers list for older adults [ 35 ]; and (2) the KIDs list for children created by the Pediatric Pharmacy Association (PPA) [ 36 ]. Table 4 outlines the medications and classes on the AGS Beers and PPA KIDs lists that should be avoided in perioperative care patients due to delirium-producing, falls-risk, reduced renal elimination, or coagulation adverse effects.…”

Section: Resultsmentioning

confidence: 99%

Positive Patient Postoperative Outcomes with Pharmacotherapy: A Narrative Review including Perioperative-Specialty Pharmacist Interviews

Parrish

Bodenstab²,

Carneal

et al. 2022

JCM

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The influence of pharmacotherapy regimens on surgical patient outcomes is increasingly appreciated in the era of enhanced recovery protocols and institutional focus on reducing postoperative complications. Specifics related to medication selection, dosing, frequency of administration, and duration of therapy are evolving to optimize pharmacotherapeutic regimens for many enhanced recovery protocolized elements. This review provides a summary of recent pharmacotherapeutic strategies, including those configured within electronic health record (EHR) applications and functionalities, that are associated with the minimization of the frequency and severity of postoperative complications (POCs), shortened hospital length of stay (LOS), reduced readmission rates, and cost or revenue impacts. Further, it will highlight preventive pharmacotherapy regimens that are correlated with improved patient preparation, especially those related to surgical site infection (SSI), venous thromboembolism (VTE), nausea and vomiting (PONV), postoperative ileus (POI), and emergence delirium (PoD) as well as less commonly encountered POCs such as acute kidney injury (AKI) and atrial fibrillation (AF). The importance of interprofessional collaboration in all periprocedural phases, focusing on medication management through shared responsibilities for drug therapy outcomes, will be emphasized. Finally, examples of collaborative care through shared mental models of drug stewardship and non-medical practice agreements to improve operative throughput, reduce operative stress, and increase patient satisfaction are illustrated.

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Pharmacist involvement to improve patient outcomes in lower gastrointestinal surgery: a prospective before and after study

Cited by 10 publications

References 17 publications

The effectiveness and safety of direct-acting antivirals for hepatitis C virus treatment: A single-center experience in Saudi Arabia

The effectiveness and safety of direct-acting antivirals for hepatitis C virus treatment: A single-center experience in Saudi Arabia

Pharmacist‐driven multidisciplinary initiative continuously improves postoperative nausea and vomiting in female patients undergoing abdominal surgery

Positive Patient Postoperative Outcomes with Pharmacotherapy: A Narrative Review including Perioperative-Specialty Pharmacist Interviews

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