Pharmaceuticals and related drugs

Gilpin, R. K.

doi:10.1021/ac50041a024

Cited by 8 publications

(4 citation statements)

References 2 publications

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“…used technique for the analysis of bulk drugs and their formulations [48]. Derivatization of the drugs prior to analysis is normally not required.…”

Section: Hplc Methods At Present Hplc Is the Most Widelymentioning

confidence: 99%

An Overview of Analytical Determination of Diltiazem, Cimetidine, Ranitidine, and Famotidine by UV Spectrophotometry and HPLC Technique

Shafi

Siddiqui

Naseem

et al. 2013

Journal of Chemistry

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This review article recapitulates the analytical methods for the quantitative determinations of diltiazem and three H2receptor antagonists (cimetidine, ranitidine, and famotidine) by one of the spectroscopic technique (UV spectrophotometery) and separation technique such as high-performance liquid chromatography (HPLC). The clinical and pharmaceutical analysis of these drugs requires effective analytical procedures for quality control, pharmaceutical dosage formulations, and biological fluids. An extensive survey of the literature published in various analytical and pharmaceutical chemistry-related journals has been compiled in its review. A synopsis of reported spectrophotometric and high-performance liquid chromatographic methods for individual drug is integrated. This appraisal illustrates that majority of the HPLC methods reviewed are based on the quantitative analysis of drugs in biological fluids, and they are appropriate for therapeutic drug monitoring purpose.

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“…used technique for the analysis of bulk drugs and their formulations [48]. Derivatization of the drugs prior to analysis is normally not required.…”

Section: Hplc Methods At Present Hplc Is the Most Widelymentioning

confidence: 99%

An Overview of Analytical Determination of Diltiazem, Cimetidine, Ranitidine, and Famotidine by UV Spectrophotometry and HPLC Technique

Shafi

Siddiqui

Naseem

et al. 2013

Journal of Chemistry

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“…Polarography has been extensively applied for the estimation of many drugs since nineteenth century (Gilpin 1979). Barker and co-workers at Harwell developed the Pulse voltammetry technique (Barker et al1952).…”

Section: Pulse Voltammetrymentioning

confidence: 99%

Electrodes for Estimation of Nimesulide Drug using Voltammetry Technique: A Revisit

Chatterjee¹

2019

stj

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Nimesulide is a pain-killer and falls in the category of non-steroidal anti-inflammatory drug. It can reduce different types of pain. Nimesulide is a safe drug but uncontrolled use of this medicine creates many problems. So detection and estimation of nimesulide is very important. Electro analytical methods are good choice for detection and estimation. Among them, voltammetry is one of the good method in this twenty-first century. In this review, different electrode materials for voltammetric study have been presented with detection limit.

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“…Methods utilizing HPLC are widely used in the QC analysis of pharmaceuticals . It offers highly selective and sensitive analytical procedures with good robustness and efficient resolution of analytes.…”

Section: Introductionmentioning

confidence: 99%

Green approach using monolithic column for simultaneous determination of coformulated drugs

Yehia

Mohamed

2016

J of Separation Science

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Green chemistry and sustainability is now entirely encompassed across the majority of pharmaceutical companies and research labs. Researchers' attention is careworn toward implementing the green analytical chemistry principles for more eco-friendly analytical methodologies. Solvents play a dominant role in determining the greenness of the analytical procedure. Using safer solvents, the greenness profile of the methodology could be increased remarkably. In this context, a green chromatographic method has been developed and validated for the simultaneous determination of phenylephrine, paracetamol, and guaifenesin in their ternary pharmaceutical mixture. The chromatographic separation was carried out using monolithic column and green solvents as mobile phase. The use of monolithic column allows efficient separation protocols at higher flow rates, which results in short time of analysis. Two-factor three-level experimental design was used to optimize the chromatographic conditions. The greenness profile of the proposed methodology was assessed using eco-scale as a green metrics and was found to be an excellent green method with regard to the usage and production of hazardous chemicals and solvents, energy consumption, and amount of produced waste. The proposed method improved the environmental impact without compromising the analytical performance criteria and could be used as a safer alternate for the routine analysis of the studied drugs.

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Pharmaceuticals and related drugs

Cited by 8 publications

References 2 publications

An Overview of Analytical Determination of Diltiazem, Cimetidine, Ranitidine, and Famotidine by UV Spectrophotometry and HPLC Technique

An Overview of Analytical Determination of Diltiazem, Cimetidine, Ranitidine, and Famotidine by UV Spectrophotometry and HPLC Technique

Electrodes for Estimation of Nimesulide Drug using Voltammetry Technique: A Revisit

Green approach using monolithic column for simultaneous determination of coformulated drugs

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