2010
DOI: 10.1007/s00216-010-4300-9
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Pharmaceutical residues in environmental waters and wastewater: current state of knowledge and future research

Abstract: Pollution from pharmaceuticals in the aquatic environment is now recognized as an environmental concern in many countries. This has led to the creation of an extensive area of research, including among others: their chemical identification and quantification; elucidation of transformation pathways when present in wastewater-treatment plants or in environmental matrices; assessment of their potential biological effects; and development and application of advanced treatment processes for their removal and/or min… Show more

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Cited by 768 publications
(360 citation statements)
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References 156 publications
(113 reference statements)
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“…PPs have been massively used and are considered emergent contaminants because they have been introduced in soils and waters through (i) human excretions in sewage collectors (especially from hospital effluents (Heberer, 2002)), (ii) disposal of unwanted, unused or expired products in the toilet or sink, and (iii) land application of animal manure (O'Connor and Aga, 2007) and treated sewage sludge (Kinney et al, 2006). PPs have been detected (at ng L − 1 and μg L − 1 levels) in a wide variety of water samples, such as effluents (from medical care units, landfills, and municipal sewage), seawater, drinking water, and surface-and groundwater, (Benotti et al, 2009;Fatta-Kassinos et al, 2011); but also in soils and sediments in concentrations ranging from μg kg − 1 to mg kg − 1 (Braganca et al, 2012;Li et al, 2012). Based on this, and to preserve drug and a priority substance that can present significant risk to or via the aquatic environment, according to the European Community (EC), Scientific Committee on Health and Environmental Risks (2011)) using green nZVIs.…”
Section: Introductionmentioning
confidence: 99%
“…PPs have been massively used and are considered emergent contaminants because they have been introduced in soils and waters through (i) human excretions in sewage collectors (especially from hospital effluents (Heberer, 2002)), (ii) disposal of unwanted, unused or expired products in the toilet or sink, and (iii) land application of animal manure (O'Connor and Aga, 2007) and treated sewage sludge (Kinney et al, 2006). PPs have been detected (at ng L − 1 and μg L − 1 levels) in a wide variety of water samples, such as effluents (from medical care units, landfills, and municipal sewage), seawater, drinking water, and surface-and groundwater, (Benotti et al, 2009;Fatta-Kassinos et al, 2011); but also in soils and sediments in concentrations ranging from μg kg − 1 to mg kg − 1 (Braganca et al, 2012;Li et al, 2012). Based on this, and to preserve drug and a priority substance that can present significant risk to or via the aquatic environment, according to the European Community (EC), Scientific Committee on Health and Environmental Risks (2011)) using green nZVIs.…”
Section: Introductionmentioning
confidence: 99%
“…In the year 2000, the US Geological Survey performed a national reconnaissance of pharmaceuticals and other organic waste water contaminants in ground and drinking water sources [54,55]. In this study, water samples were collected from a network of 47 ground water sites across 18 US States, and 65 organic compounds were analyzed.…”
Section: Analytics Of Emerging Contaminants Of Anthropomorphical Naturementioning
confidence: 99%
“…Contamination of water resources with pharmaceuticals has been one of the top concerns of environmental science in the latest years [1][2][3][4][5][6]. The widespread use of pharmaceuticals and the generally inefficient removal of such contaminants by most wastewater treatment plants (WWTPs) are the main reasons for their frequent transformation products which may be more persistent or toxic than the parent compounds if complete mineralization is not attained [2,7,8,11,12].…”
Section: Introductionmentioning
confidence: 99%