Pharmaceutical properties of macrocyclic schiff base transition metal complexes: Urgent need in Today’s World

Pharmaceutical significance of Schiff bases: an overview

“…The presence of lone pairs is attributed to its sp 2 hybridization as the compound is highly reactive due to carbon and nitrogen atoms. Due to the presence of strong properties like adaptability, simplicity, and functionality, these compounds are of high importance [11,12]. The significance is of high importance in biological assays that the Schiff bases can form diverse functional groups.…”

Synthesis, characterization, and magnetic and antibacterial properties of a novel iron(iii) complex (CH3)2NH2[Fe(phen)Cl4]

“…9,10 In addition, many drugs such as antibiotics possess better pharmaceutical properties when they are in the form of metal transition complexes. [11][12][13] From this perspective, the synthesis and characterization of new metal complexes and the evaluation of their antibacterial activities have been considered by the global community as part of the solution to overcome AMR. 14,15 Transition metal complexes with 1,10-phenanthroline ligands are of much interest since they display a wide variety of applications in organometallic chemistry, catalysis, electrochemistry, ring-opening metathesis polymerization and biochemistry.…”

Synthesis, Characterization and in vitro Antimicrobial Activity of Organotellurium Decorated 10-Membered Tetraazamacrocyclic Complexes of Cobalt(II)

“…Synthetic macrocyclic complexes can mimic some naturally occurring macrocycles due to their resemblance with natural macrocycles, such as metalloproteins and metalloenzymes [2,3]. Macrocyclic complexes have applications in the field of biometallic activation and catalysis [4], pharmaceuticals [5] and pigments and dyes [6]. Macrocyclic compounds possess very good selective complexing properties [7,8] and their metal complexes are used as catalysts [9][10][11].…”