Pharmaceutical information: A 30‐year perspective on the literature

Bawden, David; Robinson, Lyn

doi:10.1002/aris.2011.1440450109

Cited by 7 publications

(8 citation statements)

References 301 publications

(331 reference statements)

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“…The same picture can be seen for health information, which in the past had two elective modules and then a whole course devoted to it. The changing environment and changing student profile has led this subject to be treated in a similar way to business; the academic profile is maintained by staff expertise manifested in textbooks and reviews [127,128].…”

Section: And City Of London Public Librariesmentioning

confidence: 99%

Information (and library) science at City University London; 50 years of educational development

Robinson

Bawden

2010

Journal of Information Science

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This is the unspecified version of the paper.This version of the publication may differ from the final published version. Issues emerging from this analysis are discussed in seven themes: the nature of the discipline; the library/information spectrum; the student group; the academic / professional balance; curriculum design; local and global issues; and teaching methods. Permanent repository linkThe discussions of the City courses are set in the wider context of changes in library/information education over the period, in the UK and worldwide.

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Section: And City Of London Public Librariesmentioning

confidence: 99%

Information (and library) science at City University London; 50 years of educational development

Robinson

Bawden

2010

Journal of Information Science

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“…The success of the Gene Ontology (GO) as an in silico molecular biology research tool [5] suggests that drug ontologies could have a similar impact on drug research. The advance of practical ontologies into the pharmaceutical domain has been much anticipated [6–8], and is becoming evident [9, 10]. …”

Section: Introductionmentioning

confidence: 99%

Toward a comprehensive drug ontology: extraction of drug-indication relations from diverse information sources

Sharp¹

2017

J Biomed Semant

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BackgroundDrug ontologies could help pharmaceutical researchers overcome information overload and speed the pace of drug discovery, thus benefiting the industry and patients alike. Drug-disease relations, specifically drug-indication relations, are a prime candidate for representation in ontologies. There is a wealth of available drug-indication information, but structuring and integrating it is challenging.ResultsWe created a drug-indication database (DID) of data from 12 openly available, commercially available, and proprietary information sources, integrated by terminological normalization to UMLS and other authorities. Across sources, there are 29,964 unique raw drug/chemical names, 10,938 unique raw indication ”target” terms, and 192,008 unique raw drug-indication pairs. Drug/chemical name normalization to CAS numbers or UMLS concepts reduced the unique name count to 91 or 85% of the raw count, respectively, 84% if combined. Indication ”target” normalization to UMLS ”phenotypic-type” concepts reduced the unique term count to 57% of the raw count. The 12 sources of raw data varied widely in coverage (numbers of unique drug/chemical and indication concepts and relations) generally consistent with the idiosyncrasies of each source, but had strikingly little overlap, suggesting that we successfully achieved source/raw data diversity.ConclusionsThe DID is a database of structured drug-indication relations intended to facilitate building practical, comprehensive, integrated drug ontologies. The DID itself is not an ontology, but could be converted to one more easily than the contributing raw data. Our methodology could be adapted to the creation of other structured drug-disease databases such as for contraindications, precautions, warnings, and side effects.Electronic supplementary materialThe online version of this article (doi:10.1186/s13326-016-0110-0) contains supplementary material, which is available to authorized users.

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“…It is also worth noting that, for much of the period under discussion although less so at its end, the chemical information environment was very different in those industries centred on chemical research and development, and hence needing comprehensive and sophisticated access to chemical information. It was in these industries, and particularly in the pharmaceutical industry, that many developments in chemical information were pioneered, most notably structure and substructure searching systems, the systematic access and analysis of patent information, and the integration of internal and external chemical information sources through a single interface [11]. The nature of engagement with chemical information was therefore, at any time, somewhat different from that in other environments, although the general issues were much the same.…”

Section: Introductionmentioning

confidence: 99%

‘An intensity around information’: the changing face of chemical information literacy

Bawden

Robinson

2016

Journal of Information Science

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This is the accepted version of the paper.This version of the publication may differ from the final published version. Indeed, Zass [3, p. 946] reminds us that problems in practitioner use of chemical information are long-standing: "sometimes it is forgotten that these 'old times' were not as good as they now seem to be, due to the fact that many chemists lacked appropriate instruction in doing these manual searches. as they now often lack knowledge and experience to make the best use of present databases." The purpose of this paper is to examine the development of the idea of chemical information literacy over time, from the early times before the concept was described in those terms. One intention is to identify which aspects of chemical information literacy have remained constant over time, and which have emerged, disappeared, or changed with changing technologies and changing information environments. A second intention is to identify those aspects which are specific to the domain of chemistry, and those which are generic information literacy concepts which happen to appear in chemistry as in other domains. This latter is a contribution to the long-standing and on-going debate about how far there can be a generic information literacy, and how much it must always be context and subject dependent [4]. A third intention is to identify any threshold concepts of information literacy which may relate specifically to the chemistry domain. While this issue is of particular importance to academic librarians, who have been in the forefront of developing the theory and practice of information literacy, it is relevant to all information specialists dealing with subject-specific materials. Permanent repository link:

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Pharmaceutical information: A 30‐year perspective on the literature

Cited by 7 publications

References 301 publications

Information (and library) science at City University London; 50 years of educational development

Information (and library) science at City University London; 50 years of educational development

Toward a comprehensive drug ontology: extraction of drug-indication relations from diverse information sources

‘An intensity around information’: the changing face of chemical information literacy

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