2012
DOI: 10.1039/c2ce26325d
|View full text |Cite
|
Sign up to set email alerts
|

Pharmaceutical cocrystals of ethenzamide: structural, solubility and dissolution studies

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

3
56
0

Year Published

2015
2015
2023
2023

Publication Types

Select...
7
1

Relationship

0
8

Authors

Journals

citations
Cited by 72 publications
(59 citation statements)
references
References 63 publications
3
56
0
Order By: Relevance
“…[15] Salicylates are not only used as APIs, but also as cocrystal formers. [18][19][20][21][22][23]. The most popular coformer is salicylic acid with 40 cocrystals.…”
Section: Scheme 1 Molecular Structure Of Salicylates and 4-hydroxybementioning
confidence: 99%
“…[15] Salicylates are not only used as APIs, but also as cocrystal formers. [18][19][20][21][22][23]. The most popular coformer is salicylic acid with 40 cocrystals.…”
Section: Scheme 1 Molecular Structure Of Salicylates and 4-hydroxybementioning
confidence: 99%
“…Also many other physicochemical properties can be modulated by cocrystallization including stability [21][22][23][24], hygroscopicity [25] and prolonged shelf life [26]. Among many drugs, aromatic amides acting either as APIs or as excipients attract nowadays substantial attention [27][28][29][30][31][32][33][34][35]. These compounds are known for their important roles in medical applications.…”
Section: Introductionmentioning
confidence: 99%
“…Although many pharmaceutical cocrystals containing amides have been studied [27][28][29][30][31][32][33][34][35], the data deposited in the Cambridge Structural Database (CSD) [41] are rather variable in the sense that many coformers were used for synthesis of diverse cocrystals. For example cocrystals of fumaric acid with benzamide, isonicotinamide or nicotinamide are known under refcodes YOPBUB, LUNNOX and EDAPOQ, respectively, but there is no information about solids of these coformers with temozolomide.…”
Section: Introductionmentioning
confidence: 99%
“…The crystal forms are visually distinguishable as form I tends to form blocks whereas form II is needlelike. The transition between form II and form I is reportedly found between 60 and 100 °C, with a melting point of form I at 136 -140 °C [8,10,11]. The crystal structures of the two polymorphs have different conformations and can therefore be distinguished by infrared spectroscopy [8,11].…”
Section: Introductionmentioning
confidence: 98%
“…The crystal structures of the two polymorphs have different conformations and can therefore be distinguished by infrared spectroscopy [8,11]. In recent years, an increasing number of reports have appeared discussing the improvement of the physicochemical properties of CNBA with different molecules such as isonicotinic acid [12], isonicotinohydrazide [12], 3-cyanopyridine [13], 4-benzoylpyridine [14], p-anisidine [15], quinoline [16], ethenzamide [17], nicotinamide [7], pyrazine [18], mesitylene [9], p-xylene [9], acetophenone [9], dimethylsulfoxide [9], dioxane [9], 1,2,3 benzotriazole [19], including two salts: 3,5-dimethylpyridinium [20] and N'-isopropylideneisonicotinohydrazidium [12] and another compound with proton exchange in the liquid state: collidine [21]. Charge densities and other properties have also been studied for CNBA [22][23].…”
Section: Introductionmentioning
confidence: 99%