Pharmaceutical Application of Biomedical Polymers. Part XXXV. Chitosan and Sodium Alginate Based Bioadhesive Tablets for Intraoral Drug Delivery.

Oral Mucosal Adhesive Films Containing Royal Jelly Accelerate Recovery From 5-Fluorouracil^|^ndash;Induced Oral Mucositis

“…Additionally, our previous study showed that films without drugs had no effects (32). Sodium alginate is a water-soluble and swellable polymer and is an excellent candidate for delivering drugs (33,34). In fact, the sustained release of RJ from films was shown in the present study.…”

Formulation and Characterization of Glutaraldehyde Cross-Linked Chitosan Biodegradable Microspheres Loaded with Famotidine

“…Chitosan has favourable biological properties such as biodegradability, biocompatibility and non-toxicity. Chitosan was found to improve the fluidity of powder mixtures [3] and has satisfactory mucoadhesive property and good application potential [4]. Chitosan has antitumour activity, and hence chitosan microspheres bearing antineoplastic agents could be a promising carrier for cancer treatment [5].…”

Reducing fetal contamination of radiostrontium by water soluble chitosan

“…In the biomédical division, its derivatives are served as detoxicants after being poisoned by radiostrontium in the animal body (Nishimura et al, 1994}. Recently, the use of chitosan as a natural polymer of drug carriers has received much attention in the pharmaceutical field because of their good biocompatibility (Miyazaki et al, 1994). Kim et al (1996) reported that chitosan caused no chromosomal aberration, while EDTA caused significant chromosomal damage.…”