Phantom-calibrated versus automatic coronary artery mass quantification with multidetector-row computed tomography: in vitro and in vivo study

Serafin, Zbigniew; Lasek, Władysław; Laskowska, Katarzyna

doi:10.1080/02841850802314770

Cited by 4 publications

(4 citation statements)

References 26 publications

(38 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An additional advantage of this method was that it was used in this study with ECG triggering. The triggering is a standard option in the calcium scoring protocol, and significantly reduces artifacts related to heart motion [ 14 , 15 ]. As shown by Gorter et al ., measurements of fat volume by computed tomography have good reproducibility and a low coefficient of variation ranging from 3.0% to 5.0%.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Chest adipose tissue distribution in patients with morbid obesity

Lemanowicz¹,

Leszczyński²,

Rusak³

et al. 2018

Pol J Radiol

View full text Add to dashboard Cite

PurposeObesity is a well-known of risk factor for atherosclerosis and the amount of visceral adipose tissue is considered as an independent predictor of coronary artery disease (CAD). An aim of the study was to investigate the distribution of intrathoracic adipose tissue in morbidly obese patients.Material and methodsFifty-one patients with morbid obesity (BMI ≥ 40 kg/m2) and thirty controls were scanned in a coronary calcium scoring protocol. Control group consisted of patients scanned due to a clinical suspicion of CAD, who did not fulfill obesity criteria. The amount of adipose tissue was measured as epicardial adipose tissue (EAT) thickness, pericoronary fat (PCF) thickness, total intra-pericardial fat (IPF) volume, and total intrathoracic fat (ITF) volume.ResultsMean BMI of obese patients and controls was 47.3 and 26.5, respectively (p < 0.0001). Patients with obesity and controls did not differ with respect to mean EAT, mean PCF, and IPF. However, ITF was lower in obesity group than in control group (268 vs. 332 cm3, respectively; p < 0.03). Moreover, ROC analysis presented relation between obesity and the superior EAT thickness, PCF at LCX, mean PCF, ITF, and chest soft tissue (CST) thickness (p < 0.03). CST thickness of > 60 mm was the parameter that presented the strongest association with morbid obesity (AUC 0.95; p < 0.0001).ConlcusionsIncreased chest soft tissue thickness but not the increased intrathoracic adipose tissue volume was associated with morbid obesity. Since the quantity of the pericardiac fat is not directly related to the obesity, its accumulation may be related to a mechanism different than that of subcutaneous adipose tissue growth.

show abstract

Section: Discussionmentioning

confidence: 99%

“…All subjects underwent an ECG-gated cardiac CT scanning according to the coronary calcium scoring protocol using a 64-row Philips Brilliance unit [ 14 , 15 ]. No intravenous contrast media nor premedication were used.…”

Section: Methodsmentioning

confidence: 99%

Chest adipose tissue distribution in patients with morbid obesity

Lemanowicz¹,

Leszczyński²,

Rusak³

et al. 2018

Pol J Radiol

View full text Add to dashboard Cite

show abstract

“…All subjects underwent an ECG-gated cardiac CT scanning according to the coronary calcium scoring protocol using a 64-row Philips Brilliance unit [6,7]. Acquisition of data was performed in 2.5-mm slices at 120 kV and 75 mAs, with an FOV of 220 mm.…”

Section: Methodsmentioning

confidence: 99%

“…Then, the application automatically calculated Agatston’s CS. Due to the high skewness of CS values, the data were log-transformed before statistical analysis [6].…”

Section: Methodsmentioning

confidence: 99%

Coronary age, based on coronary calcium measurement, is increased in patients with morbid obesity

Lemanowicz¹,

Białecki²,

Leszczyński³

et al. 2018

Pol J Radiol

View full text Add to dashboard Cite

PurposeObesity is a well-known of risk factor for atherosclerosis. However, recently an “obesity paradox” has been discussed, which is considered as a protective effect of obesity on the development coronary artery disease (CAD). An aim of the study was to investigate the risk of CAD in morbidly obese patients using coronary artery calcium measurement.Material and methodsFifty-one patients with morbid obesity (BMI ≥ 40 kg/m2) and thirty controls were scanned to determine the amount of coronary artery calcification (CAC), which was expressed as calcium score (CS) and coronary age (CA). The control group consisted of patients scanned for the clinical suspicion of CAD, who did not fulfil the criteria of obesity.ResultsMean BMI of obese patients and controls was 47.3 and 26.5, respectively (p < 0.0001). Arterial hypertension, dyslipidaemia, and smoking were more frequent in the control group than in the obesity group (p < 0.02). The prevalence of CAC was higher in the obesity group (53% vs. 23%, p < 0.01). The groups did not differ regarding CS and CA. However, the difference between coronary age and metrical age was higher in obese patients than in controls (+5.6 vs. –4.8 years, respectively, p < 0.005).ConclusionsPatients with morbid obesity present an increased risk of CAD that is reflected by the difference between their coronary age and metrical age.

show abstract