“…Beyond the aim of this study are treatments for other certain lesions of the upper extremity and hand that are known to be associated with NF1, in particular bony alterations, e.g. erosions/osteolysis [ 47 ], [ 48 ], skeletal deformity [ 49 ], joint instability associated with PNF [ 50 ], pseudarthrosis [ 51 ], [ 52 ], [ 53 ], [ 54 ], [ 55 ], osseous local hypertrophy [ 56 ], [ 57 ], [ 58 ], [ 59 ], differentiation disorders of the hand [ 60 ], [ 61 ] including anatomical variations of hand muscles [ 62 ] and traumatic muscle disease in this entity [ 63 ]. Indeed, bone, including that in the upper limb, can be affected both locally and entirely in NF1 [ 64 ].…”