2019
DOI: 10.1016/j.ijpharm.2019.118461
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Phagocytosis of spherical and ellipsoidal micronetwork colloids from crosslinked poly(ε-caprolactone)

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Cited by 11 publications
(12 citation statements)
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“…After solvent evaporation, monodisperse precursor MP of 16.8 mm were obtained. 30 These precursor MP were embedded in PVA phantoms to subsequently conduct, in variable orders, mechanical deformation and UV-irradiation for photocrosslinking of IEMA moieties (for images see Fig. S4, ESI †).…”
Section: Micronetwork Synthesis and Propertiesmentioning
confidence: 99%
“…After solvent evaporation, monodisperse precursor MP of 16.8 mm were obtained. 30 These precursor MP were embedded in PVA phantoms to subsequently conduct, in variable orders, mechanical deformation and UV-irradiation for photocrosslinking of IEMA moieties (for images see Fig. S4, ESI †).…”
Section: Micronetwork Synthesis and Propertiesmentioning
confidence: 99%
“…Non-spherical microparticles may be produced via distinct microfabrication techniques. For the production of spheroids and ellipsoids simpler techniques such as uniaxial stretching within sacrificial templates, [102][103][104][105][106][107][108] emulsion-based, [109][110][111] superhydrophobic surface-based, 112 and conventional continuousflow microfluidic-based set-ups 113,114 have been applied. To produce other standard geometric shapes, such as cylinders, rectangular, and triangular prisms, or even more complex geometries, alternative methods have been applied.…”
Section: Microcarrier Production Methodsmentioning
confidence: 99%
“…If those materials show identical mechanical properties at the condition of deformation, they may be considered as a mechanically homogeneous elastic composite, meaning that the local flow of both polymeric materials (inclusion and phantom) occurs to an identical extent upon deformation. Based on this assumption and further considering the particles as incompressible materials of a constant volume, the stretching of a sphere with initial dimensions x 0 , y 0 and z 0 by a factor f in the x-direction should result in simultaneous thinning of the particle diameters in the yand z-directions, according to Equation (1) (homogeneous composite material model) [26].…”
Section: Deformation Models To Predict Aspect Ratiosmentioning
confidence: 99%