Phage preparation FBL1 prevents Bacillus licheniformis biofilm, bacterium responsible for the mortality of the Pacific White Shrimp Litopenaeus vannamei

Prada-Peñaranda, Catalina; Salazar, Marcela; Güiza, Linda; Pérez, María Isabel Sánchez; Leidy, Chad; Vives, Martha J.

doi:10.1016/j.aquaculture.2017.11.007

Cited by 12 publications

(2 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another area of interest for bacteriophages isolation to control different pathogens affecting production is in the field of aquaculture. These pathogens include facultative anaerobic Gram-positive bacteria such as Bacillus licheniformis [ 71 ], Lactococcus spp. and Streptococcus iniae [ 72 ].…”

Section: Bacteriophage Diversitymentioning

confidence: 99%

Phages in Anaerobic Systems

Hernández

Vives

2020

Viruses

View full text Add to dashboard Cite

Since the discovery of phages in 1915, these viruses have been studied mostly in aerobic systems, or without considering the availability of oxygen as a variable that may affect the interaction between the virus and its host. However, with such great abundance of anaerobic environments on the planet, the effect that a lack of oxygen can have on the phage-bacteria relationship is an important consideration. There are few studies on obligate anaerobes that investigate the role of anoxia in causing infection. In the case of facultative anaerobes, it is a well-known fact that their shifting from an aerobic environment to an anaerobic one involves metabolic changes in the bacteria. As the phage infection process depends on the metabolic state of the host bacteria, these changes are also expected to affect the phage infection cycle. This review summarizes the available information on phages active on facultative and obligate anaerobes and discusses how anaerobiosis can be an important parameter in phage infection, especially among facultative anaerobes.

show abstract

Section: Bacteriophage Diversitymentioning

confidence: 99%

Phages in Anaerobic Systems

Hernández

Vives

2020

Viruses

View full text Add to dashboard Cite

show abstract

“…Nonantibiotic approaches include vaccines, metabolome-reprogramming, antibiotic adjuvant, phage therapy, antibacterial peptides, and fish welfare, − where vaccine is the most promising approach due to its economy, efficacy, and safety. Vaccines elicit humoral and cellular immunities as a result of host’s immune protection responses .…”

Section: Introductionmentioning

confidence: 99%

Differential Antibody Responses to Outer Membrane Proteins Contribute to Differential Immune Protections between Live and Inactivated Vibrio parahemolyticus

et al. 2018

View full text Add to dashboard Cite

It is widely accepted that live vaccines elicit higher immune protection than inactivated vaccines. However, the mechanisms are largely unknown. Here, an array with 64 recombinant outer membrane proteins of Vibrio parahemolyticus was developed to explore antibody responses of live and inactivated V. parahemolyticus post immunization of the 8th, 12th, 16th and 20th day. Among the 64 outer membrane proteins, 28 elicited antibody generation. They were all detected in live vaccine-induced immunity but only 15 antibodies were found in inactivated vaccine-induced immunity. Passive immunization showed that higher percent survival was detected in live than inactivated vaccine-induced immunities. Active immunization indicated that out of 19 randomly selected outer membrane proteins, 5 stimulated immune protection against V. parahemolyticus infection. Among them, antibodies to VP2309 and VPA0526 were shared in mice immunized by live or inactivated vaccines, whereas antibodies to VPA0548, VPA1745, and VP1667 were only found in mice immunized by live vaccine. In addition, live V. parahemolyticus stimulated earlier antibody response than inactivated bacteria. These results indicate that not all of the outer membrane proteins elicited antibody responses when they work together in the form of live or inactivated bacteria; live vaccine elicits more protective antibodies, which contribute to higher immune protection in live vaccine than inactivated vaccine. Notably, the recombinant proteins might be different from those separated from live bacteria, and they might be different in their immunogenic potencies.

show abstract

The dawn of phage therapy

Rehman

Ali

Khan

et al. 2019

Reviews in Medical Virology

View full text Add to dashboard Cite

Bacteriophages or phages, being the most abundant entities on earth, represent a potential solution to a diverse range of problems. Phages are successful antibacterial agents whose use in therapeutics was hindered by the discovery of antibiotics. Eventually, because of the development and spread of antibiotic resistance among most bacterial species, interest in phage as therapeutic entities has returned, because their noninfectious nature to humans should make them safe for human nanomedicine.This review highlights the most recent advances and progress in phage therapy and bacterial hosts against which phage research is currently being conducted with respect to food, human, and marine pathogens. Bacterial immunity against phages and tactics of phage revenge to defeat bacterial defense systems are also summarized.We have also discussed approved phage-based products (whole phage-based products and phage proteins) and shed light on their influence on the eukaryotic host with respect to host safety and induction of immune response against phage preparations.Moreover, creation of phages with desirable qualities and their uses in cancer treatment, vaccine production, and other therapies are also reviewed to bring together evidence from the scientific literature about the potentials and possible utility of phage and phage encoded proteins in the field of therapeutics and industrial biotechnology.

show abstract

Phage preparation FBL1 prevents Bacillus licheniformis biofilm, bacterium responsible for the mortality of the Pacific White Shrimp Litopenaeus vannamei

Cited by 12 publications

References 28 publications

Phages in Anaerobic Systems

Phages in Anaerobic Systems

Differential Antibody Responses to Outer Membrane Proteins Contribute to Differential Immune Protections between Live and Inactivated Vibrio parahemolyticus

The dawn of phage therapy

Contact Info

Product

Resources

About