Phage PEf771 for the Treatment of Periapical Periodontitis Induced by Enterococcus faecalis YN771
Yingying Xiang,
Rongyu Yang,
Xuelin Li
et al.
Abstract:<i>Enterococcus faecalis </i>was the main causative bacteria of refractory periapical periodontitis (PP), there is a pressing need to explore effective methods for eradicating <i>E. faecalis </i>in patients with refractory PP. This study aimed to assess the anti-infective effectiveness of phage PEf771 in treating periapical inflammation in rats. We developed a rat model of PP through <i>E. faecalis </i>YN771 induction. Micro-computed tomography and hematoxylin-eosin staining… Show more
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