Phage cocktail alleviated type 2 diabetes by reshaping gut microbiota and decreasing proinflammatory cytokines

Ye, Jianming; Meng, Qiang; Jin, Kezhu; Luo, Yane; Yue, Tianli

doi:10.1007/s00253-023-12912-7

Cited by 4 publications

(2 citation statements)

References 71 publications

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“…10. 3389/fmicb.2024.1412991 Frontiers in Microbiology 08 frontiersin.org Wyres et al, 2020;Denamur et al, 2021;Qin et al, 2022;Ye et al, 2024). Moreover, reports have shown that Desulfovibrio, Pseudomonas, Escherichia-Shigella, and Klebsiella are also LPS-producing genera (Verhaar et al, 2020;Jia et al, 2021;Mohr et al, 2022).…”

Section: Age-dependent Dynamic Alteration Of the Functional Gut Micro...mentioning

confidence: 99%

Age over sex: evaluating gut microbiota differences in healthy Chinese populations

Wu,

Shen,

et al. 2024

Front. Microbiol.

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Age and gender have been recognized as two pivotal covariates affecting the composition of the gut microbiota. However, their mediated variations in microbiota seem to be inconsistent across different countries and races. In this study, 613 individuals, whom we referred to as the “healthy” population, were selected from 1,018 volunteers through rigorous selection using 16S rRNA sequencing. Three enterotypes were identified, namely, Escherichia–Shigella, mixture (Bacteroides and Faecalibacterium), and Prevotella. Moreover, 11 covariates that explain the differences in microbiota were determined, with age being the predominant factor. Furthermore, age-related differences in alpha diversity, beta diversity, and core genera were observed in our cohort. Remarkably, after adjusting for 10 covariates other than age, abundant genera that differed between age groups were demonstrated. In contrast, minimal differences in alpha diversity, beta diversity, and differentially abundant genera were observed between male and female individuals. Furthermore, we also demonstrated the age trajectories of several well-known beneficial genera, lipopolysaccharide (LPS)-producing genera, and short-chain fatty acids (SCFAs)-producing genera. Overall, our study further elucidated the effects mediated by age and gender on microbiota differences, which are of significant importance for a comprehensive understanding of the gut microbiome spectrum in healthy individuals.

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Section: Age-dependent Dynamic Alteration Of the Functional Gut Micro...mentioning

confidence: 99%

Age over sex: evaluating gut microbiota differences in healthy Chinese populations

Wu,

Shen,

et al. 2024

Front. Microbiol.

View full text Add to dashboard Cite

show abstract

Section: Age-dependent Dynamic Alteration Of the Functional Gut Micro...mentioning

confidence: 99%

Table_2.DOCX

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WITHDRAWN: Research on Traditional Chinese Medicine Syndrome Animal Models and Multi-omics Biomarkers in Type II Diabetes: A Review

Wang,

Gao,

Zhao

2024

Pharmacological Research - Modern Chinese Medicine

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Phage cocktail alleviated type 2 diabetes by reshaping gut microbiota and decreasing proinflammatory cytokines

Cited by 4 publications

References 71 publications

Age over sex: evaluating gut microbiota differences in healthy Chinese populations

Age over sex: evaluating gut microbiota differences in healthy Chinese populations

Table_2.DOCX

WITHDRAWN: Research on Traditional Chinese Medicine Syndrome Animal Models and Multi-omics Biomarkers in Type II Diabetes: A Review

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