Phacoemulsification with intraocular lens implantation in patients with uveitis

Suresh, P S; Jones, Nicholas P.

doi:10.1038/eye.2001.197

Cited by 61 publications

(41 citation statements)

References 29 publications

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“…Notwithstanding the accuracy imparted by angiography, this difference is large and may in part be explained by casemix differences, especially by our inclusion of patients with FHU. A lower incidence (2.3%) has also been reported 25 in a cohort of 86 eyes with uveitis undergoing phacoemulsification by one of us (NPJ), albeit with shorter follow-up. The progression of macular disease is difficult to quantify in this study.…”

Section: Discussionmentioning

confidence: 67%

“…The early postoperative results of 39 of these patients have been previously reported. 18,25 This study includes eyes with Fuchs' heterochromic uveitis. In general, reports on cataract surgery in this disease have assumed a fundamental difference between FHU and other forms of uveitis, and a better outcome is often claimed.…”

Section: Discussionmentioning

confidence: 99%

“…Cataract surgery in FHU usually passes uneventfully, but occasional substantial problems of uveitis and glaucoma arise; in some cases high-risk eyes can be identified preoperatively. 8 We have found that the use of a stringent but pragmatic approach to the preoperative treatment of inflammation 25 has enabled the reliable control of postoperative inflammation with few severe episodes of fibrinous uveitis. The return to preoperative baseline treatment in a mean 12.4 weeks (and for patients undergoing phacoemulsification, 8.6 weeks) 25 has demonstrated the safety of this approach; in this cohort, 59 eyes (82%) had returned to preoperative treatment levels within 3 months of surgery.…”

Section: Discussionmentioning

confidence: 99%

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Long-term results of cataract extraction with intraocular lens implantation in patients with uveitis

Rahman

Jones

2004

Eye

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Objective To investigate the long-term visual results after cataract extraction in patients with uveitis, and to demonstrate the long-term viability of intraocular lenses. Design In all, 61 patients (72 eyes), with update clinical examination, were retrospectively evaluated. Comparison of preoperative, postoperative, and latest visual function including best-corrected Snellen visual acuity, progression of uveitis and its complications, need for postoperative medical or surgical interventions.Results After a minimum follow-up of 5 years (mean 7 years 7 months), 82% of eyes maintained a visual improvement of two Snellen lines, 74% maintained 6/9 or better, and 14% had 6/18 or worse. The mode acuity was better than 6/6. The prevalence of macular oedema or scarring was 24%, of posterior capsule opacification 96%, and of glaucoma drainage, 15%. Conclusions We report the long-term followup of cataract extraction and intraocular lens (IOL) implantation performed by a single surgeon on patients with uveitis attending a regional tertiary referral uveitis clinic. Using stringent perioperative and postoperative control of inflammation, patients with uveitis usually maintain high visual acuity over longterm follow-up. The incidence of sightthreatening postoperative complications is low and no ongoing complication has been attributed to IOL implantation.

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Section: Discussionmentioning

confidence: 67%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Long-term results of cataract extraction with intraocular lens implantation in patients with uveitis

Rahman

Jones

2004

Eye

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“…3,5,17 Previous studies have re- ported short and long-term visual improvement of ≥ 2 lines in up to 93% of patients. [18][19][20][21] In our study, 72.4% of the eyes showed ≥ 2 Snellen lines of visual improvement at the final visit. Fuchs uveitis syndrome was associated with the best visual outcomes in our series.…”

Section: Discussionmentioning

confidence: 95%

Cataract Surgery Outcomes in Patients with Chronic or Recurrent Uveitis

Öztürk¹,

Nalçacioğlu²,

Turkyilmaz³

et al. 2018

Turkiye Klinikleri J Ophthalmol

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A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : To investigate the outcomes of phacoemulsification and posterior intraocular lens implantation (IOL) in patients with chronic or recurrent uveitis. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : The records of 84 patients, who had phacoemulsification and IOL implantation between 2010 and 2015, were retrospectively examined. The main outcomes were final visual acuity, postoperative complications, the presence of relapse, the clinical features of patients who suffered a recurrence of intraocular inflammation and the effect of triamcinolone acetonide injection into the anterior chamber during surgery on the recurrence of inflammation after cataract surgery within the first 6 months. R Re es su ul lt ts s: : The study included 109 eyes of 84 patients. The mean follow-up time was 52.6±41.8 (9-224) months. During the follow-up, posterior capsule opacification occurred in 48 (44.0%), deposits on the IOL surface in 19 (17.4%), posterior synechiae in 2 (1.8%), epiretinal membrane in 4 (3.6%), glaucoma in 7 (6.4%), and macular edema in 5 (4.5%) patients. The best corrected visual acuity with the Snellen chart at the final visit was ≤0.16 in 66.7% of serpiginous choroidopathy patients and 38% of Behçet patients. These rates were higher than with other clinical etiologies. Recurrence of uveitis within 6 months after cataract surgery occurred in 15 (13.7%) eyes. Recurrence was most common in patients with Behcet's disease. Pre-existing macular lesions were accompanied by poor visual outcomes. There was no difference between the eyes administered triamcinolone into the anterior chamber or not, regarding the frequency of attacks within the first 6 months or the postoperative complications. C Co on nc cl lu us si io on n: : Cataract surgery outcomes in patients with uveitis are satisfactory. However, patients with Behcet's disease have higher risk for relapse of intraocular inflammation and worse visual outcomes. K Ke ey yw wo or rd ds s: : Cataract; triamcinolone; uveitis; visual acuity Ö ÖZ ZE ET T A Am ma aç ç: : Kronik veya tekrarlayan üveitik hastalarda fakoemülsifikasyon ve arka kamara göz içi lensi (GİL) yerleştirilen hastaların sonuçlarını değerlendirmek. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : 2010 ila 2015 yılları arasında fakoemülsifikasyon ve arka kamara GİL'i yerleştirilen 84 hastanın kayıtları geriye dönük olarak incelendi. Sonuçların değerlendirilmesinde, sonuç görme keskinliği, cerrahi sonrası komplikasyonlar, atak varlığı, cerrahiyi takiben ilk 6 ay içerisinde atak geçiren hastaların özellik-leri ve cerrahi esnasında ön kamaraya triamsinolon verilen hastalarda inflamasyon aktivitesi üze-rine olan etkisi değerlendirildi. B Bu ul lg gu ul la ar r: : Çalışma, 84 hastanın 109 gözünü kapsamaktaydı. Ortalama takip süresi 52,6±41,8 (9-224) ay idi. Takip süresi boyunca, arka kapsül kesafeti 48 (%44,0), GİL'nin ön yüzeyinde birikim 19 (%17,4), arka sineşiler 2 (%1,8), epiretinal membran 4 (%3,6), glokom 7 (%6,4) ve maküler ödem 5 (%4,5) ...

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“…Many published series have reported excellent visual results after extracapsular cataract extraction with a rigid one-piece IOL, [1][2][3] as well as phakoemulsification using a foldable IOL. 4,5 This has been because of a combination of an improvement in microsurgical techniques including small incision surgery, the appropriate timing of the surgery, and adequate pre-, periand postoperative control of the intraocular inflammation. The biocompatibility of IOLs, or their ability to remain inert and minimise host reactions, is also of paramount importance.…”

Section: Introductionmentioning

confidence: 99%

Brown deposits in the optic of foldable intraocular lenses in patients with uveitis

Manuchehri

Mohamed

Cheung

et al. 2004

Eye

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Purpose To report a new finding of brown deposits scattered in the substance of the optic of foldable intraocular lenses (IOL) following phakoemulsification in patients with uveitis. Methods Consecutive uveitis patients (54 patients, 71 eyes) who had undergone phakoemulsification with a foldable posterior chamber IOL between March 1996 and November 2000 were studied. A variety of biomaterials from seven different manufacturers had been implanted. One masked observer using slit-lamp biomicroscopy assessed deposits in the substance of the optic of the IOL. Results Brown deposits were detected in the substance of the optic of 25/71 (35%) IOLs with 18/22 (82%) of AcrySof MA60BM IOLs being affected. Using logistic regression analysis, the AcrySof MA60BM IOL was significantly associated with the presence of deposits (adjusted odds ratio ¼ 38.5, 95% CI 6.9-200, Po0.001). Using multiple regression analysis, there was a significant association between the severity of deposits and the use of the AcrySof MA60BM IOL (P ¼ 0.005). Compared with other foldable IOLs implanted, the AcrySof MA60BM IOL was 38.5 times more likely to develop intra-IOL deposits. There was no association with those eyes that had undergone increased intraocular manipulations. The deposits did not appear to affect visual acuity. Conclusions To our knowledge the finding of brown intra-IOL deposits has not previously been described. These deposits are more frequent in the AcrySof MA60BM implant than the other foldable implants studied. They share some similarities with glistenings, but their exact nature remains unknown.

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Phacoemulsification with intraocular lens implantation in patients with uveitis

Abstract: With careful patient selection, appropriate pre-operative preparation, diligent surgery and close post-operative supervision, phacoemulsification with intraocular lens implantation is safe and effective in the great majority of eyes with uveitis.

Cited by 61 publications

References 29 publications

Long-term results of cataract extraction with intraocular lens implantation in patients with uveitis

Long-term results of cataract extraction with intraocular lens implantation in patients with uveitis

Cataract Surgery Outcomes in Patients with Chronic or Recurrent Uveitis

Brown deposits in the optic of foldable intraocular lenses in patients with uveitis

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