pH‐Responsive Torpedo‐Like Persistent Luminescence Nanoparticles for Autofluorescence‐Free Biosensing and High‐Level Information Encryption

Abstract

Persistent luminescent nanoparticles (PLNPs) with intrinsic stimuli‐responsive properties are desirable because of no autofluorescence background and natural responsive luminescence. However, the stimuli‐responsive features of pure PLNPs have been unexplored. Here we show a facile one‐pot hydrothermal synthesis of green‐emitting Zn2GeO4:Mn2+,Pr3+ nanoparticles (ZGMP) with regular shape, uniform size and good afterglow luminescent performance. We also report the pH stimuli‐responsive luminescent behavior of ZGMP and its possible mechanism. Taking the intriguing feature of pH responsive persistent luminescence, we explore ZGMP as autofluorescence‐free probes to achieve stimuli‐activated signal switch for biosensing by integrating enzyme catalysis reaction mediated pH modulation. The pH‐responsive persistent luminescence also makes ZGMP promising for high‐level information encryption.

Hydrothermal Synthesis of Zinc‐Doped Silica Nanospheres Simultaneously Featuring Stable Fluorescence and Long‐Lived Room‐Temperature Phosphorescence

“…Of particular significance,the Zn ions induced formation of defects,which can act as capture centers around oxygen vacancies to stabilize the triplet excitons,thus producing long RTPemission (lasting for % 9swith an RTPlifetime of 236 ms). Moreover,the internal Si À Obonded networks and hydrophilic surface in Zn@SiNSs can offer effective protection from environmental quenchers, leading to robust photostability under long-term UV irradiation and aw ide range of pH values (pH [1][2][3][4][5][6][7][8][9][10][11][12][13]. We believe that this aqueous synthetic strategy could open up new avenues for directly preparing novel nanomaterials,w hich simultaneously exhibit stable fluorescence and RTP.…”

“…For examples, Yan et al. reported the direct hydrothermal synthesis of pH‐responsive Zn 2 GeO 4 :Mn 2+ ,Pr 3+ persistent luminescence nanoparticles, and demonstrated their potential as auto‐fluorescence‐free nanoprobes for biosensing and information encryption [10a] . Han and co‐workers provided a straightforward template method for synthesizing persistent luminescence nanoparticles, in which In 3+ co‐doping could form a series of multicolor silica/CdSiO 3 (SCS) including SCS:In,Tb (green), SCS:In,Mn (orange), SCS:In (blue), and SCS:In,Dy (white) [10b] …”

Hydrothermal Synthesis of Zinc‐Doped Silica Nanospheres Simultaneously Featuring Stable Fluorescence and Long‐Lived Room‐Temperature Phosphorescence

“…[9] Recently,m etal ions (Zn 2+ ,M n 2+ ,P r 3+ ,I n 3+ et al)-doped inorganic matrix systems with persistent phosphorescence properties have attracted intensive attentions. [10] Fore xamples,Y an et al reported the direct hydrothermal synthesis of pH-responsive Zn 2 GeO 4 :Mn 2+ ,Pr 3+ persistent luminescence nanoparticles, and demonstrated their potential as auto-fluorescence-free nanoprobes for biosensing and information encryption. [10a] Han and co-workers provided as traightforward template method for synthesizing persistent luminescence nanoparticles,inwhich In 3+ co-doping could form aseries of multicolor silica/CdSiO 3 (SCS) including SCS:In,Tb (green), SCS:In,Mn (orange), SCS:In (blue), and SCS:In,Dy (white).…”

Encrypted and tunable graphene‐based metasurface refractive index sensor

“…Biosensors are used not only for sensing biomolecules but they are also used in encryption applications. 1,2 Biosensors are used for sensing hemoglobin (HT) and urine biomolecules. 3,4 They are also used for sensing glucose and other proteins, which is applicable in diagnostic applications.…”