pH‐Responsive Calcium Ions and Crocetin Releasing Hydrogel for Accelerating Skin Wound Healing
Li Wang,
Xuemei Ma,
Yanan Pan
et al.
Abstract:The ideal and highly anticipated dressing for skin wounds should provide a moist environment, possess antibacterial properties, and ensure sustained drug release. In the present work, a pH‐responsive hyaluronic acid‐based hydrogel (CPC@HA hydrogel) was formed by hydrogen bond and amido bond cross‐linking after introducing crocetin (Cro) and CaCO3@polyelectrolyte microspheres (CaCO3@PEM) to HA hydrogel to sustained, controlled release of the calcium ions and crocetin under slightly acid to accelerating skin wou… Show more
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