pH‐neutralizing esophageal irrigations as a novel mitigation strategy for button battery injury

Abstract

NA Laryngoscope, 2018.

Initial clinical application of tissue pH neutralization after esophageal button battery removal in children

“…However, the 0.25% acetic acid irrigation intervention is intended for use in the operating room immediately after BB removal. 15,16 This case series is the first to document multiple outcomes for the in vivo human application of intraoperative tissue pH neutralization after BB removal. There were no complications associated with the use of acetic acid irrigation in any of the patients, indicating that this may be a safe method to prevent progression of esophageal tissue injury.…”

“…Recent work demonstrated both in vitro and in vivo, using animal models that honey and sucralfate (Carafate) can be protective and help neutralize pH prior to BB removal. However, the 0.25% acetic acid irrigation intervention is intended for use in the operating room immediately after BB removal …”

Regarding pH‐neutralizing esophageal irrigations as a novel mitigation strategy for button battery injury

“…We thank Anfang et al for their results regarding the treatment of button battery (BB) injury in the last issue of The Laryngoscope. 1 Although promising, these results should be interpreted with caution.…”

In Response to pH‐Neutralizing Esophageal Irrigations as a Novel Mitigation Strategy for Button Battery Injury

“…We would like to thank Dr. Renny and colleagues for their comments related to our recent publication. 1 Although it is difficult to use an animal model to recreate the exact scenario of a pediatric esophageal button battery (BB), randomized controlled human studies are not possible. We are up against a severe hazard, a caustic BB that rapidly generates hydroxide ions, and the clock begins ticking from the moment it becomes lodged in the esophagus.…”