pH-Dependence Cytotoxicity Evaluation of Artepillin C against Tumor Cells
Wallance M. Pazin,
Renata R. Miranda,
Karina A. Toledo
et al.
Abstract:Brazilian green propolis is a well-known product that is consumed globally. Its major component, Artepillin C, showed potential as an antitumor product. This study explored the impact of Artepillin C on fibroblast and glioblastoma cell lines, used as healthy and very aggressive tumor cell lines, respectively. The focus of the study was to evaluate the pH-dependence of Artepillin C cytotoxicity, since tumor cells are known to have a more acidic extracellular microenvironment compared to healthy cells, and Artep… Show more
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