2019
DOI: 10.1016/j.jval.2019.09.1150
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Pgi27 the Burden of Non-Alcoholic Steatohepatitis (Nash) in the Eu5 Countries

Abstract: Objectives: NASH is a chronic disease that can progress to end-stage liver disease. This progression is particularly rapid in NASH patients with advanced liver fibrosis (stages F3-F4). This study estimated the disease burden and economic impact of NASH in the adult population of France, Germany, Italy, Spain and the UK.

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“…As in the United States Japan, Europe, the United Kingdom, Iran, the Middle East, and other developed and developing countries, the burden of fatty liver certainly is increased in future. 4,7,[22][23][24][25][26][27][28][29][30] The study from France, Germany, Italy, Spain, the United Kingdom, and the United States in 2018 found that the mean total cost/per patient/year for NASH was €2763, €4917, and €5509 for direct medical, direct nonmedical, and indirect costs, respectively. 23 Another study included five countries in Europe that estimated total economic costs were €8548-19 546 M. Of these, health system costs were €619-1292 M, and total well-being costs were €41 536-90 379 M. 4 This study is similar to the current study in increasing cost with the severity of the disease.…”
Section: Discussionmentioning
confidence: 99%
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“…As in the United States Japan, Europe, the United Kingdom, Iran, the Middle East, and other developed and developing countries, the burden of fatty liver certainly is increased in future. 4,7,[22][23][24][25][26][27][28][29][30] The study from France, Germany, Italy, Spain, the United Kingdom, and the United States in 2018 found that the mean total cost/per patient/year for NASH was €2763, €4917, and €5509 for direct medical, direct nonmedical, and indirect costs, respectively. 23 Another study included five countries in Europe that estimated total economic costs were €8548-19 546 M. Of these, health system costs were €619-1292 M, and total well-being costs were €41 536-90 379 M. 4 This study is similar to the current study in increasing cost with the severity of the disease.…”
Section: Discussionmentioning
confidence: 99%
“…As in the United States Japan, Europe, the United Kingdom, Iran, the Middle East, and other developed and developing countries, the burden of fatty liver certainly is increased in future. 4 , 7 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 The study from France, Germany, Italy, Spain, the United Kingdom, and the United States in 2018 found that the mean total cost/per patient/year for NASH was €2763, €4917, and €5509 for direct medical, direct nonmedical, and indirect costs, respectively. 23 …”
Section: Discussionmentioning
confidence: 99%