PET+MR versus PET/CT in the initial staging of head and neck cancer, using a trimodality PET/CT+MR system

Use of MRI and FDG‐PET/CT to predict fixation of advanced hypopharyngeal squamous cell carcinoma to prevertebral space

“…Multivariate logistic regression demonstrated that the best model for prediction of PVS involvement is the presence fat plane obliteration. This corresponds well to the findings of Hsu et al A recent study by Sekine et al compared the diagnostic accuracy of FDG‐PET/CT and FDG‐PET/MR for the assessment of tumor resectability in a mixed cohort of advanced HNSCC . Among other resectability‐defining factors, they compared the ability of both modalities to diagnose PVS involvement.…”

“…This corresponds well to the findings of Hsu et al 10 A recent study by Sekine et al compared the diagnostic accuracy of FDG-PET/CT and FDG-PET/MR for the assessment of tumor resectability in a mixed cohort of advanced HNSCC. 6 Among other resectability-defining factors, they compared the ability of both modalities to diagnose PVS involvement. They reported a positive predictive value, negative predictive value, and accuracy of 87.5%, 98%, and 98.3% for FDG-PET/CT and 100%, 100%, and 100% for FDG-PET/MR, respectively.…”

“…With the recent introduction of FDG‐PET/MR, some CT‐related problems in the oropharynx that also exist in FDG‐PET/CT, for example, dental artifacts, could be improved. For assessing the resectability of the primary tumor, several studies showed that both hybrid imaging modalities—FDG‐PET/CT and FDG‐PET/MR—are reliable tools . The clinical assessment of HNSCC usually relies on triple endoscopy, which incorporates an examination of the upper aerodigestive tract with rigid or flexible instruments under general anesthesia and a systematic digital palpation of the pivotal subsites.…”

“…For assessing the resectability of the primary tumor, several studies showed that both hybrid imaging modalities-FDG-PET/CT and FDG-PET/MRare reliable tools. [5][6][7] The clinical assessment of HNSCC usually relies on triple endoscopy, which incorporates an examination of the upper aerodigestive tract with rigid or flexible instruments under general anesthesia and a systematic digital palpation of the pivotal subsites. Thereby, the location and extent of the primary tumor is assessed, and synchronous second malignancies are found in 6.4%-12% of patients.…”

PET/CT versus PET/MRT bei Kopf-Hals-Tumoren

“…Eine erste kleine Studie von Kanda et al, die die retrospektive Fusion von PET-und MRT-Datensätzen untersuchte, zeigte Vorteile für die PET/MRT im T-Staging [33]. Auch Studien von anderen Forschungsgruppen, die am ehesten aufgrund der ge-ringen Probandenzahl keinen statistisch signifikanten Vorteil der PET/MRT gegenüber der PET/CT zeigen konnten, wiesen einen positiven Trend für die PET/MRT auf [34,35]. Auch zeigte sich in einer Studie von Sekine et al aus dem Jahre 2017 ein geringer, wenn auch nicht statistisch signifikanter Trend zu einer besseren Beurteilbarkeit der Resezierbarkeit in der PET/MRT [36].…”