PET-CT scan in a patient with Kikuchi disease

The Role of PET/CT in the Diagnosis of Kikuchi-Fujimoto Disease: A Case Series and Review of the Literature

“…We reviewed 13 cases from previous eight studies and 3 cases from our study (Tables 2 and 3) [12][13][14][15][16][17][18]. From these 16 cases it was reported that 15 out of 16 cervical lymph nodes (bilateral in 8 patients, and unilateral in 8 patients), 7 out of 16 axillary lymph nodes (bilateral in 5 patients, and unilateral in 2 patients), 6 of 16 mediastinal lymph nodes, and 2 of 16 inguinal lymph nodes exhibited increased FDG uptake, while 4 of the 16 patients had matted extra-peritoneal lymph nodes.…”

Kikuchi disease: 18F-FDG positron emission tomography/computed tomography of lymph node uptake

“…In particular, the SUVs of FDG PET images are useful for diagnosing malignancy, whereas several case reports have suggested that the lymph nodes of patients with KD exhibit FDG avidity. 2,9,10 Indeed, our study showed that KD was diffi cult to distinguish from malignant lymphoma using only the PET/CT fi ndings in the present series, even when evaluated retrospectively. However, FDG-PET/CT seemed to help with some clinical decisions regarding the exclusion of metastasis and the involvement of extranodal sites in malignant lymphoma.…”

“…Nevertheless, this limitation is unlikely to have affected our conclusion as previous case reports were consistent with our results. 2,9 Conclusion Distinguishing KD from other diseases with cervical lymph node swelling is rather diffi cult. However, if the distribution of FDG-avid lymph nodes and the size of the affected lymph nodes on FDG-PET/CT images are considered in addition to the physical fi ndings and the patient's age, FDG PET/CT images may be useful as indicators of possible KD.…”

“…Recently, a few cases of FDG-PET/CT fi ndings in patients with KD have been reported. 2,9,10 These reports have suggested that patients with KD exhibit a high FDG uptake in their lymph nodes. However, there have been no systematic FDG-PET/CT studies of patients with KD reported.…”

Kikuchi-Fujimoto disease mimicking tuberculous lymphadenitis or lymphoma on fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography

“…In recent years, usefulness and usage of 18F-FDG PET in KFD has been reported. It has been shown that in KFD, lymph nodes have an uptake of FDG similar to aggressive lymphoma [9][10][11] and other chronic granulomatous diseases like tuberculous lymphadenitis. This study can help clinicians to identify the severity of the disease through extension of lymph node involvement.…”