PET/CT in the evaluation of patients with squamous cell cancer of the head and neck

Goshen, Elinor; Davidson, Tima; Yahalom, Ran; Talmi, Yoav P.; Zwas, S. Tzila

doi:10.1016/j.ijom.2005.08.003

Cited by 31 publications

(13 citation statements)

References 19 publications

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“…All these 11 findings had SUVs less than 4.0. Similar findings were noted in a study by Goshen et al [11], where equivocal findings were found to be insignificant on follow up. Studies directed toward correlating SUVs and presence of disease will further increase the accuracy and applicability of PET.…”

Section: Discussionsupporting

confidence: 90%

“…In a prospective study by Connell et al [12], there was a 34% change in TNM classification, a 29% change in radiotherapy planning and/or dose and altered treatment response assessment in 43%, when PET-CTwas added to other conventional techniques of imaging. In the other two studies, PET-CT impacted patient management in 12% and 16% of patients, respectively [3,11]. Our study findings are similar to these studies, indicating a definite role of PET-CT in making treatment decisions for patients with recurrent head and neck cancers.…”

Section: Discussionsupporting

confidence: 86%

“…There have been only a few studies assessing change in management in patients with suspected recurrent head and neck cancers [3,11,12]. In a prospective study by Connell et al [12], there was a 34% change in TNM classification, a 29% change in radiotherapy planning and/or dose and altered treatment response assessment in 43%, when PET-CTwas added to other conventional techniques of imaging.…”

Section: Discussionmentioning

confidence: 99%

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PET‐CT in recurrent head neck cancers: A study to evaluate impact on patient management

Pantvaidya

Agarwal

Deshpande

et al. 2009

Journal of Surgical Oncology

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Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 86%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

PET‐CT in recurrent head neck cancers: A study to evaluate impact on patient management

Pantvaidya

Agarwal

Deshpande

et al. 2009

Journal of Surgical Oncology

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“…According to the reports of Goshen et al18, PET-CT examination has 88% accuracy, 100% sensitivity, and 77% specificity. When it came to negative predictive value from patients who showed metastasis, it was found to be 100%.…”

Section: Discussionmentioning

confidence: 99%

The impact factors on 5-year survival rate in patients operated with oral cancer

Geum

Roh

Yoon

et al. 2013

J Korean Assoc Oral Maxillofac Surg

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ObjectivesThe purpose of this study is to analyze clinical impact factors on the survival rate, and to acquire basic clinical data for the diagnosis of oral cancer, for a determination of the treatment plan with long-term survival in oral cancer patients.Materials and MethodsThrough a retrospective review of the medical records, the factors for long-term survival rate were analyzed. Thirty-seven patients, among patient database with oral cancer treated in the Department of Oral and Maxillofacial Surgery at Pusan National University Hospital within a period from March 1998 to March 2008, were selected within the study criteria and were followed-up for more than 5 years. The analyzed factors were gender, age, drinking, smoking, primary tumor site, type of cancer, TNM stage, recurrence of affected region, and metastasis of cervical lymph node. The 5-year survival rate on the impact factors was calculated statistically using the Kaplan-Meier method.ResultsBy classification of clinical TNM at the 1st visit, there were 11 (29.7%) cases for stage I, 11 (29.7%) cases for stage II, 3 (8.1%) cases for stage III, and 12 (32.5%) cases for stage IV. The 5-year survival rate of total oral cancer patients after the operation were 75.7%, pathological TNM stage related 5-year survival rate were as follows: stage I 90.0%, stage II 81.8%, stage III 100% and stage IV 45.5%; in which the survival rate difference by each stage was significantly observed. The recurrence of cervical lymph node was the significant impact factor for the survival rate, because only 30.0% the survival rate in recurrent cases existed. During the follow-up, there were 15 (40.5%) patients with confirmed recurrence, and the 5-year survival rate of these patients was decreased as 46.7%.ConclusionThe classification of clinical and pathological TNM stage, local recurrence after surgery, and metastasis of cervical lymph node after surgery were analyzed as the 3 most significant factors.

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“…The development of integrated PET-CT has overcome some of these problems, providing additional information in 18–20% of patients compared to PET alone [8, 9] however bone invasion is better identified with contrast enhanced CT [10] nevertheless PET-CT may be helpful in defining the extent of tumour better than CT alone especially in post surgical cases. Lesions are considered suspicious for malignancy if the SUV is greater than 2.5–3, although inflammatory lesions may have similar values and variable physiologic uptake may cause some problems.…”

Section: Staging the Primary Tumourmentioning

confidence: 99%

PET in face and neck tumours

Rankin

2006

Cancer Imaging

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PET/CT in the evaluation of patients with squamous cell cancer of the head and neck

Cited by 31 publications

References 19 publications

PET‐CT in recurrent head neck cancers: A study to evaluate impact on patient management

PET‐CT in recurrent head neck cancers: A study to evaluate impact on patient management

The impact factors on 5-year survival rate in patients operated with oral cancer

PET in face and neck tumours

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