Pesticides and Health Risks

Gilden, Robyn; Huffling, Katie; Sattler, Barbara

doi:10.1111/j.1552-6909.2009.01092.x

Cited by 392 publications

(207 citation statements)

References 32 publications

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“…Sometimes pesticides are also used even after the harvest of the crop. The presence of pesticide residues is a concern for consumers as they pose toxic effects such as interfering with the reproductive systems and foetal development as well as their capacity to cause cancer and asthma (Gilden et al, 2010). The analysis of pesticide residues is an important concern due to their high toxicity and the serious risk that they represent for the human health and environment.…”

Section: Introductionmentioning

confidence: 99%

Detection of Methyl Parathion Residues in Vegetables by Using Chromogenic Reagent

Easwari¹,

Jayakumar²

2017

Int.J.Curr.Microbiol.App.Sci

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Section: Introductionmentioning

confidence: 99%

Detection of Methyl Parathion Residues in Vegetables by Using Chromogenic Reagent

Easwari¹,

Jayakumar²

2017

Int.J.Curr.Microbiol.App.Sci

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“…They are applied on the ground, in the air, and in divers products. 4) During World War II, in 1941, organophosphates were reintroduced worldwide for pesticide purposes, as originally intended. The extensive use of pesticides has affected human health.…”

Section: Introductionmentioning

confidence: 99%

Enzymatic detoxification of organophosphorus pesticides and related toxicants

Alejo-González

Hanson-Viana

Vázquez-Duhalt

2018

Journal of Pesticide Science

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Millions of cases of pesticide intoxication occur yearly and represent a public health problem. In addition, pesticide poisoning is the preferred suicidal method in rural areas. The use of enzymes for the treatment of intoxication due to organophosphorus pesticides was proposed decades ago. Several enzymes are able to transform organophosphorus compounds such as pesticides and nerve agents. Some specific enzymatic treatments have been proposed, including direct enzyme injection, liposome and erythrocytes carriers, PEGylated preparations and extracorporeal enzymatic treatments. Nevertheless, no enzymatic treatments are currently available. In this work, the use of enzymes for treating of organophosphorus pesticide intoxication is critically reviewed and the remaining challenges are discussed.

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“…Their effects being mainly via contamination of food [2]. Children are more prone to accidental poisoning by such products [7,8].…”

Section: Introductionmentioning

confidence: 99%

Effect of Ethanol Leaf Extract of Moringa oleifera on Oxidative Stress and Atherogenic Indices of Otapiapia-Exposed Albino Rats

Igwe¹,

Nwaogu²,

Ezeokeke³

et al. 2017

J Clinic Toxicol

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Objective: Otapiapia is a locally produced, easily accessible, non-regulated household pesticide, which could easily contaminate human food. The ameliorative effect of ethanol leaf extract of Moringa oliefera on otapiapiainduced changes in oxidative stress, lipid profile and atherogenic indices of albino rats was investigated using standard methods.Methodology: Twenty-four apparently healthy Wister male albino rats (150-180 g) were divided into 4 groups (I-IV) of 6 animals each. Group I served as the control, while group II animals were given otapiapia contaminated feed and distilled water. Group III were fed uncontaminated diet and M. oleifera extract drink. Group IV animals were also given the contaminated diet and M. oliefera extract. The feed and drinks were provided ad libitum for a period of 14 days. Result:The results show that intake of otapiapia significantly (p<0.05) reduced serum superoxide dismutase and catalase activities and HDL-c concentration but increased significantly (p<0.05) the concentrations of malondialdehyde, total cholesterol, triacylglycerol, LDL-c and VLDL-c. The derangements were significantly more pronounced in the atherogenic predictor indices than with lipid profile values. The observed effects of otapiapia were significantly (p<0.05) countered by administration of M. oliefera leaf extract. Conclusion:The results indicate that M. oleifera is a potent anti-poison with ameliorative effect against otapiapia-induced changes in biomarkers of oxidative and atherogenic damages in animals.

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Pesticides and Health Risks

Cited by 392 publications

References 32 publications

Detection of Methyl Parathion Residues in Vegetables by Using Chromogenic Reagent

Detection of Methyl Parathion Residues in Vegetables by Using Chromogenic Reagent

Enzymatic detoxification of organophosphorus pesticides and related toxicants

Effect of Ethanol Leaf Extract of Moringa oleifera on Oxidative Stress and Atherogenic Indices of Otapiapia-Exposed Albino Rats

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