Pesticide Informatics Platform (PIP): An International Platform for Pesticide Discovery, Residue, and Risk Evaluation

Abstract

Pesticides are widely used agrochemicals for crop protection. The need for novel pesticides becomes urgent as a result of the emergence of resistance and environmental toxicity. Pesticide informatics has been applied in different phase processes of pesticide target identification, active ingredient design, and impact evaluation. However, these valuable resources are scattered over the literature and web, limiting their availability. Here, we summarize and connect research on pesticide informatics resources. A pesticide informatics platform (PIP) was constructed to share these tools. We finally discuss the future direction of pesticide informatics, including pesticide contamination. We expect to share the pesticide informatics approaches and stimulate further research.

Self-Assembled Sphere Covalent Organic Framework with Enhanced Herbicidal Activity by Loading Cyhalofop-butyl

“…Pesticides are widely used to control pests, fungus, and weeds worldwide. However, these pesticides negatively affect the public health, safety, and ecological systems. − For instance, some commercial formulations, such as emulsifiable concentrates, wettable powders, and suspension concentrates, suffer from short effective periods and low utilization rates. The resulting repeated use of high-dose pesticide formulations leads to the accumulation of high residues and harmful organic solvents, which cause environmental risks .…”

Rapid and sensitive detection of chlordimeform in cucumber and tomato samples using an immunochromatographic assay

“…In agriculture, pesticides are used to control diseases and pests and regulate plant growth. 1,2 However, most pesticides are toxic and can be passed through the food chain, negatively impacting human health. 3,4 Chlordimeform (CDM) is a formamidine acaricide widely used to control pests in important crops and farmed animals, and has a significant effect compared with other pesticides.…”

Optimization of Osthole in the Lactone Ring as an Agrochemical Candidate: Synthesis, Characterization, and Pesticidal Activities of Osthole Amide/Ester Derivatives and Their Effects on Morphological Changes of Mite Epidermis

“…1−4 Tetranychus cinnabarinus Boisduval (Acari: Tetranychidae) is one of the most harmful mites in the world of agriculture and forest production, with a short life history, high reproductive capacity, and high resistance to many chemical active ingredients. 5−8 Blind pesticide abuse frequently occurs in an effort to increase crop yields, and manage pests and illnesses, which results in the emergence of pest resistance 9,10 and major environmental pollution issues. 11−14 Obviously, the development of new pesticides is still on the way.…”