diseases and vaccine development with bacmid (bacterial artificial chromosomes containing the baculovirus genome) technology is one of its most important features (O'Reilly et al. 1992;Miller et al. 1998).Baculoviruses are subject to various classifications according to both their nucleo-capsid structure and the host group they infect. Baculoviruses with polyhedrin protein are called nucleopolyhedrovirus, and those with granulin protein are called granuloviruses. Nucleopolyhedroviruses are determined to have a single or multiple nucleocapsid structure as a result of transmission electron microscopy examinations (Ackermann and Smirnoff 1983). Although the majority of baculoviruses infect the Lepidoptera group (Alphabaculoviruses and Betabaculoviruses), there are also isolates that infect Hymenoptera (Gamabaculoviruses) and Diptera (Deltabaculoviruses) (Jehle et al. 2006).In recent years, molecular comparison of baculovirus isolates has been done at the whole genome level. In particular, genomic differences between baculovirus isolates obtained from dissimilar geographical regions are understood by Gozde Busra Eroglu