Pesquisas sôbre o Endotrypanum schaudinni Mesnil e Brimont, 1908, parasita do Choloepus didactylus (L)

Cunha, Aristides Marques da; Muniz, Julio

doi:10.1590/s0074-02761944000400010

Cited by 5 publications

(2 citation statements)

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“…Despite Trypanosoma spp. being one of the most common hemoparasite genera in wildlife [83][84][85][86] and its repeated identification in multiple sloth species [3,54,[87][88][89], we identified it only in C. hoffmanni. For microfilaria species, they were previously reported in M. niger and N. nasua.…”

Section: Hemoparasite Animalmentioning

confidence: 99%

Vector-borne zoonotic blood parasites in wildlife from Ecuador: A report and systematic review

et al. 2021

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Background and Aim: Ecuador is a hugely diverse country, but information on infectious diseases in local wild animals is scarce. The aim of this study was to screen the presence of blood parasites in free-ranging wild animals admitted to the Wildlife Hospital at Universidad San Francisco de Quito, from April 2012 to January 2019. Materials and Methods: We identified blood parasites by microscopic observation of blood smears from free-ranging wildlife species that attended the Wildlife Hospital of Universidad San Francisco de Quito (Ecuador) from April 2012 to January 2019. Results: The microscopic evaluations of animals as potential reservoirs for vector-borne zoonotic blood parasites revealed the presence of Anaplasma spp., Babesia spp., Ehrlichia spp., Hepatozoon spp., microfilaria, Mycoplasma spp., and Trypanosoma spp. in previously unreported wildlife species. In addition, we performed a systematic review to understand the current knowledge gaps in the context of these findings. Conclusion: Our data contribute to the knowledge of blood parasites in wildlife from Ecuador. Furthermore, the potential transmission of these parasites to humans and domestic animals, current anthropogenic environmental changes in the region, and the lack of information on this suggest the importance of our results and warrant further investigations on infectious diseases in animals and humans and their relationship with environmental health as key domains of the One Health concept.

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Section: Hemoparasite Animalmentioning

confidence: 99%

Vector-borne zoonotic blood parasites in wildlife from Ecuador: A report and systematic review

et al. 2021

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“…Its intracellular localization was subsequently confirmed using electron microscopy [ 15 ]. This species turned out to be very unusual, as the intra-erythrocytic forms were represented by epimastigotes, while, in culture, only promastigotes, reminiscent of Leishmania spp., could be observed [ 16 ]. This led to a suggestion that the two morphotypes belong to distinct lineages, of which the intra-erythrocytic parasite represents an unidentified trypanosome, while the cultured forms are related to Leishmania [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

Genome Analysis of Endotrypanum and Porcisia spp., Closest Phylogenetic Relatives of Leishmania, Highlights the Role of Amastins in Shaping Pathogenicity

Albanaz

Gerasimov

Shaw

et al. 2021

Genes

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While numerous genomes of Leishmania spp. have been sequenced and analyzed, an understanding of the evolutionary history of these organisms remains limited due to the unavailability of the sequence data for their closest known relatives, Endotrypanum and Porcisia spp., infecting sloths and porcupines. We have sequenced and analyzed genomes of three members of this clade in order to fill this gap. Their comparative analyses revealed only minute differences from Leishmaniamajor genome in terms of metabolic capacities. We also documented that the number of genes under positive selection on the Endotrypanum/Porcisia branch is rather small, with the flagellum-related group of genes being over-represented. Most significantly, the analysis of gene family evolution revealed a substantially reduced repertoire of surface proteins, such as amastins and biopterin transporters BT1 in the Endotrypanum/Porcisia species when compared to amastigote-dwelling Leishmania. This reduction was especially pronounced for δ-amastins, a subfamily of cell surface proteins crucial in the propagation of Leishmania amastigotes inside vertebrate macrophages and, apparently, dispensable for Endotrypanum/Porcisia, which do not infect such cells.

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Evolution of nuclear DNA and the occurrence of sequences related to new small chromosomal DNAs in the trypanosomatid genus Endotrypanum

Lopes

Iovannisci

Petrillo-Peixoto

et al. 1990

Molecular and Biochemical Parasitology

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Pesquisas sôbre o Endotrypanum schaudinni Mesnil e Brimont, 1908, parasita do Choloepus didactylus (L)

Cited by 5 publications

References 0 publications

Vector-borne zoonotic blood parasites in wildlife from Ecuador: A report and systematic review

Vector-borne zoonotic blood parasites in wildlife from Ecuador: A report and systematic review

Genome Analysis of Endotrypanum and Porcisia spp., Closest Phylogenetic Relatives of Leishmania, Highlights the Role of Amastins in Shaping Pathogenicity

Evolution of nuclear DNA and the occurrence of sequences related to new small chromosomal DNAs in the trypanosomatid genus Endotrypanum

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