Pervasive Developmental Disorder in Monozygotic Twins

Objective: To review the current knowledge on neurobiological aspects of autism and pervasive developmental disorders, as well as to provide pediatricians with up to date information on diagnosis and treatment of autism. Sources of data: Review of MEDLINE and Internet.Summary of the findings: Autism is the 3rd developmental disorder, with an incidence of 40 to 130/100,000 individuals. Diagnosis is based on clinical findings, following DSM IV criteria. Neuroimaging, investigation of fetal neurological status, and genetic investigation contribute towards a better understanding of the neurobiology of autism. Conclusion:Pediatricians are the first health professional to come in contact with patients with autism. Thus, they should be able to diagnose and to coordinate the multidisciplinary treatment of these patients.J Pediatr (Rio J). 2004;80(2 Suppl):S83-S94: Autism, child behavior, child development.

show abstract

“…Although multiple chromosomes have been implicated in autism, no definitive answer has been found. [97][98][99] …”

Section: Neurochemistrymentioning

confidence: 99%

Autismo e doenças invasivas de desenvolvimento

Gadia¹,

Tuchman²,

Rotta³

2004

J. Pediatr. (Rio J.)

119

View full text Add to dashboard Cite

show abstract

“…Autismo é um transtorno genético complexo e, com base nos baixos escores obtidos nos estudos colaborativos de genoma, tem sido sugerido que entre 5 a 100 loci possam estar envolvidos na suscetibilidade para TEA. Embora múltiplos cromossomas tenham sido implicados com autismo, nenhuma resposta definitiva foi encontrada [97][98][99] .…”

Section: Genéticaunclassified

Autism and pervasive developmental disorders

Gadia¹,

Tuchman²,

Rotta³

2004

J Pediatr (Rio J)

View full text Add to dashboard Cite

Objective: To review the current knowledge on neurobiological aspects of autism and pervasive developmental disorders, as well as to provide pediatricians with up to date information on diagnosis and treatment of autism. Sources of data: Review of MEDLINE and Internet. Summary of the findings: Autism is the 3rd developmental disorder, with an incidence of 40 to 130/100,000 individuals. Diagnosis is based on clinical findings, following DSM IV criteria. Neuroimaging, investigation of fetal neurological status, and genetic investigation contribute towards a better understanding of the neurobiology of autism. Conclusion: Pediatricians are the first health professional to come in contact with patients with autism. Thus, they should be able to diagnose and to coordinate the multidisciplinary treatment of these patients.

show abstract

Section: Genéticaunclassified