Pertlymph Oxygenation in Sudden and Progressive Sénsorineural Hearing Loss

Nagahara, Kunihiko; Fisch, Ugo; Yagi, Nobuya

doi:10.3109/00016488309132875

Cited by 70 publications

(42 citation statements)

References 3 publications

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“…Moreover, arterial hypertension may cause ionic changes in cell potentials, resulting in hearing loss. 58,59 It is possible that hypertension could, through such factors, cause hearing impairment, and consequently, it would be expected that workers exposed to high noise levels and having hypertension would be more prone to hearing impairment and hearing loss. 59 The occurrence of hearing impairment in our exposed population was not associated with hypertension.…”

mentioning

confidence: 99%

Angiotensin-converting enzyme gene polymorphisms and hypertension in occupational noise exposure in Egypt

Zawilla

Shaker

Abdelaal

et al. 2014

International Journal of Occupational and Environmental Health

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Background: The gene-environment interaction in the pathogenesis of hypertension has not been extensively studied in occupational noise. Objectives: The aim of this study was to determine the relationship between noise and hypertension in Egyptian workers, the interaction of angiotensin-converting enzyme (ACE) gene polymorphisms as modifiers, and the possible relationship between noise hearing impairment and hypertension. Methods: Study subjects were divided into two groups depending on noise exposure level. The control group (n5161) was exposed to noise intensity ,85 dB and the exposed group (n5217) was exposed to noise intensity §85 dB. A polymerase chain reaction was used to differentiate the various genotypes of ACE insertion/deletion (I/D) and ACE G2350A. Results: Noise significantly increased the likelihood of hypertension. Carriers of the genotypes AG, GG, and DD were vulnerable to hypertension on noise exposure. No association between hypertension and hearing impairment or noise-induced hearing loss (NIHL) was found. Conclusion: Our results support the association between ACE gene polymorphisms and occurrence of hypertension in noise-exposed workers.

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confidence: 99%

Angiotensin-converting enzyme gene polymorphisms and hypertension in occupational noise exposure in Egypt

Zawilla

Shaker

Abdelaal

et al. 2014

International Journal of Occupational and Environmental Health

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“…[11] It was found that perilymphatic oxygen tension decreased in patients with SSNHL, while under hyperbaric conditions, oxygen tension in the perilymphatic fluid increased by 450% [12,13] . These days, HBO therapy is used as primary or as salvage therapy for sudden haring loss [14][15][16] .…”

Section: Introductionmentioning

confidence: 99%

Hyperbaric Oxygen Therapy as Salvage Therapy for Sudden Sensorineural Hearing Loss

Ajduk¹,

Ries²,

Trotić³

et al. 2017

Int Adv Otol

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OBJECTIVE:To measure the effect of hyperbaric oxygen (HBO) therapy as salvage therapy after the failure of steroid therapy for sudden sensorineural hearing loss (SSNHL). MATERIALS and METHODS:Ninety-three patients with SSNHL were unsuccessfully treated with systemic steroid therapy. Following steroid therapy, 43 patients received additional HBO therapy while 50 did not. Hearing levels at 0.25, 0.5, 1, 2, 4, and 8 kHz before and after therapy were measured. RESULTS:A significant difference in hearing thresholds after HBO therapy was found at all frequencies in patients with a hearing loss of >61 dB. The group of patients with a hearing threshold of ≤60 dB had a significant improvement only at 250 and 500 Hz, while group of patients without additional therapy control group showed no hearing improvement. CONCLUSION:Hyperbaric oxygen therapy therapy as salvage therapy for SSNHL showed some benefits in hearing improvement. Better results could be expected in patients with severe hearing loss, while in patients with mild-or-moderate hearing loss, recovery should be expected only at low frequencies.

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“…Hypertension, the most common vascular disorder, may facilitate structural changes in the heart and blood vessels. High pressure in the vascular system may cause inner ear hemorrhage, which is supplied by the anterior inferior cerebellar artery, which supports the inner ear artery and is divided into cochlear artery and anterior vestibular artery [4], which may cause progressive or sudden hearing loss [3,5]. This circulatory system pathology may directly affect hearing in a number of ways.…”

Section: Introductionmentioning

confidence: 99%

Effects of Hypertension on Hearing

Agarwal

Mishra

Jagade

et al. 2013

Indian J Otolaryngol Head Neck Surg

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To determine the likely association between hypertension and hearing loss. 150 cases and 124 controls, both genders, aged 45-64, included in the research after sample estimation. Hypertension was verified through blood pressure readings and was classified as grade 1, grade 2 and grade 3 hypertension or no hypertension according to the blood pressure readings. Hearing was assessed by measuring pure tone threshold at various frequencies ranging between 250 and 8,000 Hz. There is a significant association between hypertension and increase in the hearing threshold. Hearing loss in the population under study suggests that hypertension is an accelerating factor of degeneration of the hearing apparatus due to aging. Association between Increased hearing threshold and hypertension in this research, can allow for an integrated work of cardiologists, nephrologists, otorhinolaryngologists, audiologists and other health professionals concerned with alterations caused by hypertension.

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Pertlymph Oxygenation in Sudden and Progressive Sénsorineural Hearing Loss

Cited by 70 publications

References 3 publications

Angiotensin-converting enzyme gene polymorphisms and hypertension in occupational noise exposure in Egypt

Angiotensin-converting enzyme gene polymorphisms and hypertension in occupational noise exposure in Egypt

Hyperbaric Oxygen Therapy as Salvage Therapy for Sudden Sensorineural Hearing Loss

Effects of Hypertension on Hearing

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